GSC 235:  Graduate School for Computing in Medicine and Life Sciences

• Subject Area: Systems Engineering ; Neurosciences
• Term: from 2007 to 2014
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 39133334

• Final Report Year: 2015

Final Report Abstract

The Graduate School for Computing in Medicine and Life Sciences was established in 2007, funded within the Excellence Initiative of the German Governments. It links the three main fields of research of the university: medicine, computer science and life sciences. All main facilities are located on one campus. More than 67 fully funded doctoral students from 15 countries are currently enrolled, during the whole time the graduate school had 114 doctoral candidates. The scientific programme of the school has found widespread recognition, and the school is now a leading research centre in several fields. Among these fields are optical coherence tomography, magnetic particle imaging, as well as research on memory and sleep. The interdisciplinary structures implemented by the school have sharpened the research focus of the university, and internal administrative structures were simplified. Directly following the implementation of the graduate school, the role of the university senate has been changed, and the administrative boundaries between departments were removed. The senate is now responsible for all doctoral affairs, which reflects the close interdisciplinary collaboration within the new doctoral programmes. An incentive programme for attracting third-party funding was set up during the first phase. With this programme, the school has attracted a substantial amount of external funding, and more than 90 percent of student stipends now stem from external sources. Now, 28 percent of the doctoral students enrolled and 52 percent of students successfully graduated are women, which is particularly impressive for a graduate programme in engineering. The Graduate School GS-CMLS will continue its successful work as a permanent institution of the University. Meanwhile, the University of Lübeck has established an additional institution – the Graduate School Lübeck - GSL, to continue and expand the original Graduate School. This new expanded GSL is based on the structure of the original graduate school, and implements all structures first established by the original graduate school (such as structured PhD programs, fast track PhD programs, tenure-track options, and gender equality and equal opportunity measures). The new GSL acts as a university-wide roof organization in the graduation sector, and expands all new measures implemented by the graduate school to the entire university. Overall, the graduate school has had a substantial impact on the kernel of the university structure as a whole. It has transformed main elements of the university, such as the basic faculty structure. It has established modern structured PhD programs with dedicated quality assurance measures and thereby helps to develop international standards for PhD education.

Link to the final report

http://dx.doi.org/10.2314/GBV:882355864

Publications

• Tomographic imaging using the nonlinear response of magnetic particles, Nature, vol. 435, no. 7046, 1214-1217, June 2005
  Gleich B, Weizenecker J
  
• Adult pancreatic stem/progenitor cells spontaneously differentiate in vitro into multiple cell lineages and form teratoma-like structures. Ann Anat 188(6), 503-17, 2006
  Kruse C, Kajahn J, et al.
  
• Boosting slow oscillations during sleep potentiates memory. Nature 444, 610-613, 2006
  Marshall L, Helgadóttir H, Mölle M, Born J
  
• EEG analysis using wavelet-based information tools. J. Neurosci. Meth. 153, 163-182, 2006
  Rosso OA, Martin MT, Figliola A, Keller K, Plastino A
  
• Electrical High Frequency Stimulation Induces Gaba Outflow in Freely Moving Rats. J. Neurosci. Methods, 159(2), 286-290, 2007
  Hiller A, Loeffler S, Haupt C, Litza M, Hofmann UG, Moser A
  
• The upshot of up states in the neocortex: from slow oscillations to memory formation. J Neurosci 27, 11838-11841, 2007
  Hoffman KL, Battaglia FP, Harris K, MacLean JN, Marshall L, Mehta MR
  
• Functional connectivity of reward processing in the brain. Front Hum Neurosci 2(19), 2008
  Camara E, Rodriguez-Fornells A, Münte T
  
• Imaging of Cancer Cells using Gold Nanoparticels and Fluorescent Dyes by Multiphoton Micros-copy, J. Biomed. Opt. 13, 031217, 2008
  Qu X, Wang J, Zhang Z, Koop N, Rahmanzadeh R, Hüttmann G
  
• Neuropsychological and psychiatric changes after deep brain stimulation for Parkinsons disease: a randomized, multicentre study, Lancet Neurol 7, 605-614, 2008
  Witt K, Daniels C, Reiff J, Krack P, Volkmann J, Pinsker MO, Krause M, Tronnier V, Kloss M, et al.
  
• A Fast Algorithm for Nonequispaced Fourier Transforms on the Rotation Group, Numer. Algorithms 52, 355-384, 2009
  Potts D, Prestin J, Vollrath A
  
• Comparison of Cornea Module and DermaInspect for non-invasive imaging of ocular surface pathologies, J. Biomed. Opt., 2009
  Steven P, Müller M, Koop N, Rose C, Hüttmann G
  
• Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat Biotechnol., 27(3):275-80, 2009
  Chambers SM, et al.
  
• Modeling the hypothalamus-pituitary-adrenal system: homeostasis by interacting positive and negative feedback. J Biol Phys 35, 149- 162, 2009
  Conrad M, Hubold C, Fischer B, Peters A
  
• New susceptibility locus for coronary artery disease on chromosome 3q22.3, Nat Genet. 41(3), 280-282, 2009
  Erdmann J, et al.
  
• Reward networks in the brain as captured by connectivity measures. Front Neurosci 3, 350-362, 2009
  Camara E, Rodriguez-Fornells A, Ye Z, Münte T
  
• Slow oscillation electrical brain stimulation during waking promotes EEG theta activity and memory encoding. Proc Natl Acad Sci USA 106, 15460-15465, 2009
  Kirov R, Weiss C, Siebner HR, Born J, Marshall L
  
• Compact energy metabolism model: brain controlled energy supply. J Theor Biol 264, 1214-1224, 2010
  Goebel B, Langemann D, Oltmanns KM, Chung M
  
• In vivo Fourier-domain fullfield OCT of the human retina with 1.5 million A-lines/s, Opt. Lett. 35, 3432-3434, 2010
  Bonin T, Franke G, Hagen-Eggert M, Koch P, Hüttmann G
  
• Microstructural brain differences predict functional hemodynamic responses in a reward processing task. J Neurosci, 30, 11398- 11402, 2010
  Camara E, Rodriguez-Fornells A, Münte T F
  
• Optical coherence tomography with online visualization of more than seven rendered volumes per second. J Biomed Opt, 15:026014, 2010
  Probst J, Hillmann D, Lankenau E, Winter C, Oelckers S, Koch P, Hüttmann G
  
• The memory function of sleep. Nat Rev Neurosci 11, 114-126, 2010
  Diekelmann S, Born J
  
• Brain stimulation during sleep, J Sleep Med Clin. 6(1), 85-95, 2011
  Marshall L, Born J
  
• Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet 43, 333-338, 2011
  Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, O'Donnell CJ, McPherson R, Erdmann J, Samani NJ, et al.
  
• Mitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 iPS cells. J Neurosci, 31, 5970-5976, 2011
  Seibler P, Graziotto J, Heong H, Simunovic F, Klein C, Krainc D
  
• Westermann Defining the quantitative limits of intravital two-photon lymphocyte tracking. Proc Natl Acad Sci USA. 2011 Jul 6
  J. Textor, A. Peixoto, S. E. Henrickson, M. Sinn, U.H. von Andrian , J.