Cell-cell interactions controlling organ shape (B06)

• Subject Area: Developmental Biology
• Term: since 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 386797833

Using zebrafish primordial germ cells (PGCs) as a model, we will study the mechanisms by which migrating cells sense and respond to physical and cellular cues that position them at the correct places during organ formation. To this end, we are establishing a framework for deriving morphological features and for following the dynamic localization of organelles and molecules within the cells. We will study changes in these parameters in response to interactions with different structures that PGCs encounter in their environment.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1348: Dynamic cellular interfaces: formation and function
• Applicant Institution: Universität Münster
• Project Heads: Professor Dr. Erez Raz; Dr. Katsiaryna Tarbashevich, until 12/2021