Project Details
Projekt
Characterization and modeling of mechanical stresses in cellular aggregates during bioprinting (B07)
Subject Area
Biomaterials
Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
Statistical Physics, Nonlinear Dynamics, Complex Systems, Soft and Fluid Matter, Biological Physics
Term
since 2018
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 326998133
Mechanical stresses due to shear and extensional flows during biofabrication can negatively affect functionality and viability of printed cells. Using synthetic sensor particles as well as computer simulations, B07 investigates how these stresses arise and how they can be minimized by propor choices of printing conditions. In the third phase, B07 focusses in particular on the mechanics of cells in larger aggregates, so-called spheroids.
DFG Programme
CRC/Transregios
Applicant Institution
Julius-Maximilians-Universität Würzburg
Project Heads
Dr. Krystyna Albrecht, until 12/2025; Professor Dr. Andreas Fery, until 12/2021; Professor Dr. Stephan Gekle; Professor Dr. Jürgen Groll, since 1/2026; Professor Dr. Georg Papastavrou, since 1/2022
