Co-evolution of gut microbiota and immune cells during ageing in killifish (B04)

• Subject Area: Evolution, Anthropology
• Term: since 2018
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 325931972

Project B4 will experimentally track the evolution of immune repertoires and microbes in killifish, a model organism of vertebrate ageing. We will map age-dependent changes in host immune function and use them to predict ecology and evolution of host-associated microbial communities, specifically the emergence of pathogenic strains and their impact on the ageing process.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1310: Predictability in Evolution
• Applicant Institution: Universität zu Köln
• Project Heads: Dr. Handan Melike Dönertas, since 1/2022; Professor Dr. Dario Riccardo Valenzano, Ph.D.