Effects of obesity and anti-obesity treatments on pancreatic cancer (P08)

• Subject Area: Gastroenterology
• Term: from 2018 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 329628492

This project aims to understand the impact of obesity, diet, caloric restriction and gastric sleeve surgery on formation and progression of PDAC. Mechanistic studies include the detailed characterization of inter-organ communication between adipose tissue and the tumor mediated by inflammatory adipokines and extracellular vesicles. The long-term aim is to develop novel prevention and treatment strategies tailored towards obese patients.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1321: Modelling and Targeting Pancreatic Cancer
• Applicant Institution: Technische Universität München (TUM)
• Project Heads: Professorin Dr. Kerstin Stemmer; Professor Dr. Matthias Tschöp