Functional Role of the Hippo Pathway Coactivator Taz in the Aging of Hematopoietic Stem Cells

• Applicant: Dr. Björn von Eyss
• Subject Area: Cell Biology
• Term: from 2018 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 409619902

• Final Report Year: 2022

No abstract available

Publications

• A comprehensive transcriptome signature of murine hematopoietic stem cell aging. Blood, 138(6), 439-451.
  Flohr, Svendsen Arthur; Yang, Daozheng; Kim, KyungMok; Lazare, Seka; Skinder, Natalia; Zwart, Erik; Mura-Meszaros, Anna; Ausema, Albertina; von Eyss, Björn; de Haan, Gerald & Bystrykh, Leonid
  
• Taz protects hematopoietic stem cells from an aging-dependent decrease in PU.1 activity. Nature Communications, 13(1).
  Kim, Kyung Mok; Mura-Meszaros, Anna; Tollot, Marie; Krishnan, Murali Shyam; Gründl, Marco; Neubert, Laura; Groth, Marco; Rodriguez-Fraticelli, Alejo; Svendsen, Arthur Flohr; Campaner, Stefano; Andreas, Nico; Kamradt, Thomas; Hoffmann, Steve; Camargo, Fernando D.; Heidel, Florian H.; Bystrykh, Leonid V.; de Haan, Gerald & von Eyss, Björn