Formation of the repressed nanos mRNP in the early Drosophila embryo

• Applicant: Professor Dr. Elmar Wahle
• Subject Area: General Genetics and Functional Genome Biology ; Biochemistry
• Term: from 2019 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 427447367

No abstract available

Publications

• Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Reports, 31(12), 107783.
  Cao, Wen Xi; Kabelitz, Sarah; Gupta, Meera; Yeung, Eyan; Lin, Sichun; Rammelt, Christiane; Ihling, Christian; Pekovic, Filip; Low, Timothy C.H.; Siddiqui, Najeeb U.; Cheng, Matthew H.K.; Angers, Stephane; Smibert, Craig A.; Wühr, Martin; Wahle, Elmar & Lipshitz, Howard D.
  
• In Vitro Reconstitution of the Drosophila melanogaster CCR4-NOT Complex to Assay Deadenylation. Methods in Molecular Biology (c(2023, 10, 13)), 19-45. Springer US.
  Pekovic, Filip & Wahle, Elmar
  
• RNA binding proteins Smaug and Cup induce CCR4–NOT-dependent deadenylation of the nanos mRNA in a reconstituted system. Nucleic Acids Research, 51(8), 3950-3970.
  Pekovic, Filip; Rammelt, Christiane; Kubíková, Jana; Metz, Jutta; Jeske, Mandy & Wahle, Elmar