Post-resection therapy in patients with metastatic colorectal Cancer (PORT) AIO KRK01418

• Applicant: Professor Dr. Dominik Modest
• Subject Area: Hematology, Oncology ; General and Visceral Surgery
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 427928818

The PORT (FIRE9) trials aims to establish additive/adjuvant therapy after definitive treatment of metastatic colorectal cancer. Currently the standard of care in the national guidelines is "structured follow-up". The hypothesis of the trial is a clinically relevant improvement of progression-free survival by the addition of 6 months systemic chemotherapy. Secondary endpoints of the trial include overall survival, quality of life, toxcity, efficacy in molecular subgroups and further translational work-up.

• DFG Programme: Clinical Trials
• Co-Investigators: Professor Dr. Volker Heinemann; Professor Dr. Johann Pratschke; Professor Dr. Nathanael Raschzok; Professor Dr. Igor Maximilian Sauer; Professor Dr. Sebastian Stintzing