Improving the Matteson Homologation for Natural Product Syntheses

• Applicant: Professor Dr. Uli Kazmaier
• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 2020 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 439145210

The goal of this project is to develop the Matteson Homologation as a general tool for the stereoselective synthesis of natural products. The existing tool box should be expanded by using functionalized building blocks, giving access to a range of different classes of natural products (amino acids, peptides, polyketides, macrolides, …). The new developed protocols will directly be applied in total syntheses to evaluate and demonstrate their scope and limitations.

• DFG Programme: Research Grants