Targeting the Ag85 Complex in Mycobacteria

• Applicant: Privatdozentin Dr. Claudia Jessen-Trefzer
• Subject Area: Biological and Biomimetic Chemistry ; Pharmacy
• Term: since 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 444119567

This project envisions investigating the mycobacterial membrane space and to find new potential drugs, which are covalent inhibitors of the enyzm komplex Ag85. The project describes the developement of a live cell screening assay based on fluorgenic Ag85 substrates.

• DFG Programme: Research Grants