Project Details
Projekt
The effects of nasal esketamine and treatment expectation in acute major depressive disorder: a pharmacological fMRI study (A08)
Subject Area
Biological Psychiatry
Term
since 2020
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 422744262
Pharmacological fMRI will be used in combination with a fully balanced placebo design to investigate psychological and neural mechanisms underlying the antidepressant effects of positive treatment expectation in patients with major depression, and how these effects combine or interact with acute antidepressant effects of the NMDA receptor antagonist esketamine. Prefrontal, limbic, and reward circuitry will be of special interest.
DFG Programme
CRC/Transregios
Applicant Institution
Universität Duisburg-Essen
Project Heads
Privatdozentin Dr. Irina Falkenberg; Professor Dr. Tilo Kircher
