Expectation-induced enhancement of treatment effects on pain, itch and quality of life in psoriasis patients (A12)

• Subject Area: Personality Psychology, Clinical and Medical Psychology, Methodology
• Term: since 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 422744262

We will systematically modulate treatment expectation in psoriasis patients undergoing treatment with the anti-IL-17A monoclonal antibody secukinumab in a clinical proof-of-concept trial. We will determine the effects of expectation induced by verbal instruction on treatment outcomes at the subjective (e.g., pain, itch, quality of life) and physiological (e.g., skin lesions) levels and will analyze whether and to what extent such strategy can be employed to reduce the treatment dosage.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 289: Treatment Expectation - The impact of expectation on health outcome
• Applicant Institution: Universität Duisburg-Essen
• Project Heads: Professor Dr. Manfred Schedlowski; Privatdozentin Dr. Wiebke Sondermann