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On the revision of negative expectations in people with depressive symptoms - A series of two experimental investigations

Subject Area Personality Psychology, Clinical and Medical Psychology, Methodology
Term from 2020 to 2024
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 449791349
 
Final Report Year 2025

Final Report Abstract

People with depressive symptoms have difficulty correcting established negative views when they have new positive experiences. The process of cognitive immunisation is being discussed as a new mechanism for this unfavourable information processing: According to this, positive experiences that contradict negative expectations are subsequently devalued or reinterpreted. The aim of the project was to investigate the influence of cognitive immunisation on the correction of negative expectations in people with depression in two experimental studies. For this purpose, established experimental paradigms of depression research were used, which were slightly modified for this project: Study 1 examined the change in negative performance expectations through positive performance feedback, while Study 2 looked at the change in negative future expectations and therapy expectations through positive experience reports from other patients. In both studies, cognitive immunisation was promoted in one experimental condition and inhibited in another. In addition, there was a distraction control condition and a control condition without instruction. As an additional research question, both subprojects investigated whether there were differences between people with episodic (MDE) vs. persistent depressive disorder (PDD) in the change in negative expectations and in the response to the respective experimental manipulations. In study 1, 139 people with diagnosed depressive disorder were included (n = 63 with MDE and n = 76 with PDD). The results show that there were no significant differences between the experimental groups with regard to the change in negative performance expectations. In Study 2 (N = 156, of which n = 102 with MDE and n = 54 with PDD), there was also no significant difference overall between the experimental conditions in the change in negative future expectations, although there were unexpected gender differences here. With regard to the comparison of MDE vs. PDD, there were no significant differences in the context of performance expectations (Study 1), but there were significant differences with regard to the change in treatment expectations (Study 2): Thus, people with MDE adjusted their therapy expectations relatively strongly after viewing the positive experience reports, whereas this change was significantly weaker in people with PDD. The results of Study 2 also show that people with PDD responded particularly strongly to the manipulation to promote cognitive immunisation and changed their treatment expectations very little, especially in this experimental condition. The project results suggest that although cognitive immunisation may indeed be a relevant factor with regard to the failure to correct negative expectations in depression, its significance must be considered in a differentiated manner.

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