Compartmentalization of Light-induced Reactions in DNA-Liposome Hybrid Structures (B08)

• Subject Area: Inorganic Molecular Chemistry - Synthesis and Characterisation ; Biological and Biomimetic Chemistry
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 364549901

B08 develops lipid bilayer liposome vesicles surface-functionalized with DNA assemblies as anchoring sites for molecular PSs (focus: metal complexes and organic dyes) and CATs (focus: HER and CO2-activation). This architecture will facilitate exposure of the reactive sites to the aqueous reaction phase, while enabling precise arrangement of PS and CAT by DNA assembly strategies. The bilayer membrane will be tuned as large light-harvesting antenna to funnel light energy towards the catalyst. DNA nanotechnology will allow embedding of various PS/CAT combinations and enable energy and electron-transfer tuning, while liposome vesicles will facilitate compartmentalization of photochemical reactions.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 234: Light-driven Molecular Catalysts in Hierarchically Structured Materials – Synthesis and Mechanistic Studies
• Applicant Institution: Friedrich-Schiller-Universität Jena
• Project Heads: Professorin Dr. Andrea Pannwitz; Professorin Dr. Tanja Weil, since 7/2022