Implant safety through individualisation of revision and regeneration of primary prosthetic components (A01)

• Subject Area: Orthopaedics, Traumatology, Reconstructive Surgery ; Metal-Cutting and Abrasive Manufacturing Engineering
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 426335750

This subproject covers in an exemplary manner the entire process from detection of implant failure to individualized technical regeneration. For the first time, a comprehensive digital implant lifecycle management (DILM) system will be set up. Based on the DILM architecture established in the first funding period, patient-specific data from various implant systems will be integrated to enhance personalized implant care via data-driven prediction models. Using the example of total knee arthroplasty, research will focus on methods for reproducible, non-invasive condition-based evaluation of implant components in the digital twin, radiological wear marker detection, and automated revision path planning.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 298: Safety Integrated and Infection Reactive Implants
• Applicant Institution: Medizinische Hochschule Hannover
• Project Heads: Professor Dr.-Ing. Berend Denkena; Privatdozent Dr.-Ing. Marc-André Dittrich, until 11/2023; Professor Dr. Max Ettinger, until 11/2024; Dr. Lars-René Tücking; Dr.-Ing. Marcel Wichmann, until 12/2025