Receptor-like cytoplasmic kinase-mediated control of pattern-triggered immunity (D10*)

• Subject Area: Organismic Interactions, Chemical Ecology and Microbiomes of Plant Systems ; Plant Biochemistry and Biophysics
• Term: since 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 232631280

Plants employ surface-resident LRR receptor kinases (LRR-RKs) and LRR receptor proteins (LRR-RPs) to activate pattern-triggered immunity (PTI). Receptor-like cytoplasmic kinase PBL31 associated with LRR-RP-complexes, EDS1 PAD4 heterodimers and helper NLR (hNLR) of the ADR1-type form a signaling platform that is essential for LRR-RP-mediated PTI, but is only partially required for LRR-RK-mediated PTI activation. In this project, we will address the molecular basis of PBL31-mediated regulation of LRR-RP-induced PTI and whether LRR-RP-complexes and the EDS1 PAD4 ADR1 signaling platform are arranged in close physical proximity at the inner plasma membrane.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1101: Molecular Encoding of Specificity in Plant Processes
• Applicant Institution: Eberhard Karls Universität Tübingen
• Project Head: Professor Dr. Thorsten Nürnberger