Project Details
Projekt
Dynamics of membrane receptor clustering in endothelial cells (P07)
Subject Area
Molecular Biology and Physiology of Neurons and Glial Cells
Term
since 2022
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 450648163
The spatial organization of transmembrane receptors is a critical step in propagation of signals and receptor trafficking in cells. In project P07, we will specifically characterize the dynamic spatial arrangement of ephrinB homotypic and heterotypic complexes with its partners by super-resolution microscopy. We will also investigate how these arrangements are regulated at the membrane, recruiting cytosolic adaptors to achieve a variety of efficient functional outcomes.
DFG Programme
Collaborative Research Centres
Applicant Institution
Goethe-Universität Frankfurt am Main
Project Head
Professorin Dr. Amparo Acker-Palmer
