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Probing multiprotein assemblies with native mass spectrometry (P13)

Subject Area Biochemistry
Term since 2022
Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 450648163
 
Mitochondrial ATPases are of high relevance for (human) life. In project P13, we will probe changes in the ATP synthase complex formation in correlation to mutations causing neuropathological diseases by native mass spectrometry. In addition, we want to investigate different mechanistic principles, which control recruitment of specific phospholipids or lipopolysaccharides. To advance these aims, we will push boundaries regarding the use of membrane mimics for native mass spectrometry.
DFG Programme Collaborative Research Centres
 
 

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