High-throughput hyperpolarization (B02)

• Subject Area: Analytical Chemistry
• Term: since 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 454252029

This proposal explores three strategies to increase the throughput of dissolution-based hyperpolarization methodologies by up to two orders of magnitude. The first strategy explores Pulsed DNP at temperatures from 1.5 to 100 K using a pulsed 100 W 95 GHz Klystron amplifier. The second high-risk/high-gain strategy uses freely rotating methyl groups (which exhibit a rotational splitting equal to that of a free electron spin at approximately 4 Tesla) as a source for hyperpolarization. The third strategy uses the recently emerged photo-radicals as a source of hyperpolarization.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1527: High Performance Compact Magnetic Resonance – HyPERiON
• Applicant Institution: Karlsruher Institut für Technologie
• Project Head: Dr. Benno Meier