Project Details
Projekt
Infection-induced germline and somatic mutation rates of resistance genes (A06)
Subject Area
Plant Genetics and Genomics
Term
since 2023
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 491090170
Resistance genes are known for their high genetic diversity. However, it is not clear whether they mutate more frequently or whether there is a strong diversifying selection pressure acting on these loci. Increased mutation rates could be mediated by homologous recombination, which is specific to regions with local duplications and increased upon pathogen infection. In consequence pathogen infection could lead to increased mutation rates specifically in genes encoding a response to exactly this stress. We will test this hypothesis by analysing the actual germline and somatic mutation rates in plants grown with and without pathogen pressure.
DFG Programme
CRC/Transregios
Applicant Institution
Ludwig-Maximilians-Universität München
Project Head
Professor Dr. Korbinian Schneeberger
