Endotheliale Vorläuferzellen bei Organtransplantation - Autologe und allogene T-Zell-Aktivierung, Immunmodulation und therapeutischer Einsatz zur Gefäßprotektion

• Applicant: Dr. Thomas J. Dengler
• Subject Area: Cardiology, Angiology
• Term: from 2000 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5286190

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Endothelial-cell dependent CD8+ T cell activation by human endothelial ICOSL. Eur J Immunol 2005; 35(6):1712-1721
  Klingenberg R, Gleissner C, Wambsganss N, Richter G, Giese T, Katus HA, Dengler TJ
  
• IL-10 inhibits endothelium-dependent T-cell costimulation by upregulation of ILT3/4 in human vascular endothelial cells. Eur J Immunol 2007 ;37(l):177-92
  Gleissner CA, Zastrow A, Klingenberg R, Sivanandam V, Celik S, Giese T, Kluger M, Katus HA, Dengler TJ
  
• Platelet-associated LIGHT (TNFSF14) mediates adhesion of platelets to human vascular endothelium. Thromb Haemostas 2007; 98(4):798-805
  Celik S, Langer H, Stellos K, May AE, Shankar V, Kurz K, Katus HA, Gawaz MP, Dengler TJ
  
• Sphingosine-1-Phosphate Analogue FTY720 Causes Lymphocyte Redistribution and Hypercholesterolemia in ApoE-Deficient Mice. Arterioscler Thromb Vase Biol. 2007; 27(11):2392-9
  Klingenberg R, Nofer JR, Rudling M, Bea F, Blessing E, Preusch M, Grone HJ, Katus HA, Hansson GK, Dengler TJ
  
• TCR Signaling Antagonizes Rapid IP-10- Mediated Transendothelial Migration of Effector Memory CD4+ T Cells. J Immunol 2007; 178(5):3237-43
  Manes TD, Shiao SL, Dengler TJ, Pober JS
  
• Endothelial progenitor cells possess monocyte-like antigen-presenting and T cell-activating capacity Transplantation
  S. Vijayshankar, P. Rämer, S. Hämmerling, M. Konstandin, S. Celik, T. Giese, H.A. Katus, T.J. Dengler
  
• Proinflammatory and prothrombotic effects on human vascular endothelial cells of immunecell-derived LIGHT
  Celik S, Shankar V, Richter A, Hippe HJ, Bea F, Erbel C, Urban S, Blank N, Wambsganss N, Katus HA, Dengler TJ