Project Details
Projekt
Rewiring of GABAergic inhibitory cells recruited during spatial encoding (B02)
Subject Area
Cognitive, Systems and Behavioural Neurobiology
Term
since 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 514483642
In this project we aim to characterize which structural and functional changes the inhibitory network undergoes, in the CA1 region of the hippocampus, due to spatial encoding. Therefore, we will perform recordings in slices and in freely moving animals, where we will optogenetically interfere with spatial encoding, to study the functional modifications of activated neurons and their interneuron circuits. We will further use large-scale 3D electron microscopy and array tomography to examine the resultant structural modifications in the hippocampal circuits.
DFG Programme
CRC/Transregios
Applicant Institution
Albert-Ludwigs-Universität Freiburg
Project Heads
Dr. Matthias Haberl; Dr. Silvia Viana da Silva, Ph.D.
