Sekundärstrukturbildung in Peptiden mit nicht-proteinogenen Aminosäuren

• Antragsteller: Professor Dr. Hans-Jörg Hofmann
• Fachliche Zuordnung: Biochemie
• Förderung: Förderung von 2001 bis 2010
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5330707

• Erstellungsjahr: 2010

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• Helices in peptoids of a- and ß-peptides. Phys. Biol. 3 (2006) SI-S9
  Baldauf, C ; Günther, R.; Hofmann. H.-J.
  
• Helix formation in a,y- and ß,y-hybrid peptides: Theoretical insights into mimicry of a- and ß-peptides. J. Org. Chem. 71 (2006) 1200-1208
  Baldauf, C; Günther, R.; Hofmann, H.-J.
  
• Theoretical prediction of the basic helix types in a,ß-hybrid peptides. Biopolymers 84 (2006) 408-413
  Baldauf. C : Günther. R.: Hofmann. H.-J.
  
• BlNOL-based foldamers - Access to oligomers with diverse structural architectures. J. Org. Chem. 72 (2007) 5077-5084
  Baruah, P.K.; Gonnade, R.; Rajamohanan, P. R.; Hofmann, H.-J.: Sanjayan, G. J.
  
• Enforcing periodic secondary structures in hybrid peptides: A novel hybrid foldamer containing periodic y-turn motifs. J. Org. Chem. 72 (2007) 636-639
  Baruah, P. K.; Sreedevi, N. K.; Gonnade, R.; Ravindranathan, S.; Damodaran,K.; Hofmann. H.-J.; Sanjayan, G. J.
  
• Synthesis and secondary structure of alternate a,ß-hybrid peptides containing oxazolidin-2-one moieties. Eur. J. Org. Chem. 2007, 2713-2721
  Angelici, G.; Luppi, G.; Kaptein, B.; Broxterman, O. B.; Hofmann. H.-J.: Tomasini, C.
  
• A fiber-like peptide material stabilized by single intermolecular hydrogen bonds. Angew. Chem. Int. Ed. 47 (2008) 8075-8078
  Angelici, G.; Falini, G.; Hofmann, H.-J.: Huster, D., Monari, M.; Tomasini, C.
  
• Artificial chemokines: Combining chemistry and molecular biology for the elucidation of interleukin-8 functionality. J. Am. Chem. Soc. 130 (2008) 15311 -15317
  David, R.; Günther, R.; Baumann, L.; Lühmann, T.; Seebach, D.; Hofmann, H.-J.; Beck-Sickinger, A. G.
  
• Foldamers with unusual structural architecture from spirobi(indane) building blocks. Chem. Comm. 2008 (22), 2541-2543
  Kendhale, A. M.; Gonnade, R.; Rajamohanan, P. R.; Hofmann. H.-J.; Sanjayan, G. J.
  
• Sequence-specific unusual (1->2)-type helical turns in a/ß-hybridpeptides. J. Am. Chem. Soc. 130 (2008), 17743-17754
  Prabhakaran, P.; Kale, S. S.; Puranik, V. G.; Rajamohanan, P. R.; Chetina, O.; Howard, J. A. K.; Hofmann. H.-J.: Sanjayan, G. J.
  
• Helix formation in e-amino acid oligomers. J. Mol. Struct. (Theochem) 907 (2009) 109-114
  Schramm, P.: Hofmann, H.-J.
  
• Hybrid helices: Motifs for secondary structure scaffolds in foldamers. J. Am. Chem. Soc. 131 (2009) 17335-17344
  Sharma, G. V. M.; Chandramouli, N.; Choudhary, M.; Nagendar, P.; Ramakrishna, K. V. S.; Kunwar, A. C ; Schramm, P.; Hofmann. H.-J.
  
• Nanofibers from oxazolidi-2-one containing hybrid foldamers: What is the right molecular size? Chem. Eur. J. 15 (2009) 8037-8048
  Angelici, G.; Falini, G.; Hofmann. H.-J.: Huster, D.; Monari, M.; Tomasini, C.
  
• Novel foldamer structural architecture from cofacial aromatic building blocks. Chem. Commun. 2009, 3446-3448
  Prabhakaran, P.; Puranik, V. G.; Chandran, J. N.; Rajamohanan, P. R.; Hofmann. H.-J.: Sanjayan, G. J.
  
• Sterically controlled naphthalene homo-oligoamides with novel structural architectures. Org. Biomol. Chem. 7 (2009) 2458-2465
  Prabhakaran, P.; Puranik, V. G.; Chandran, J. N.; Rajamohanan, P. R.; Hofmann, H.-J.: Sanjayan, G. J.
  
• Synthesis and structure of a/ö-hybr\ö peptides - access to novel helix patterns in foldamers. Chem. Eur. J.; 15 (2009) 5552-5566
  Sharma, G. V. M.; Babu, B. S.; Ramakrishna, K. V. S.; Nagendar, P.; Kunwar, A. C ; Schramm, P.; Baldauf, C ; Hofmann. H.-J.
  
• Theoretical and experimental studies on a/e-hybrid peptides: Design of a 14/12-helix from peptides with alternating (S)-C-linked carbo-e-amino acid [(S)- e-Caa((x))] and L-Ala. J. Org. Chem. 74 (2009) 6703-6713
  Sharma, G. V. M.; Babu, B. S.; Chatterjee, D.; Ramakrishna, K. V. S.; Kunwar, A. C ; Schramm, P.; Hofmann, H.-J.
  
• A network of small molecules connected by cross-linked NH bonds. Cryst. Growth. Design 10 (2010) 244-251
  Angelici, G.; Castellucci, N.; Contaldi, S.; Falini, G.; Hofmann. H.-J.: Monari, M.; Tomasini, C.
  
• Double helix formation in a-peptides: A theoretical study. J. Pept. Sci. 2010
  Schramm, P.; Hofmann, H.-J.
  
• Helix formation in ß/6-hybrid peptides: Correspondence between helices of different peptide foldamer classes. Biopolymers 2010
  Schramm, P.; Hofmann, H.-J.