Analyse des Netzwerks von Hitzestresstranskriptionsfaktoren von Arabidopsis thaliana

• Antragsteller: Professor Dr. Lutz Nover
• Fachliche Zuordnung: Biochemie und Biophysik der Pflanzen
• Förderung: Förderung von 2001 bis 2004
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5352758

The complexity of the plant stress response systems correlates with an unusual multiplicity of regulatory proteins. Analysis of the Arabidopsis genome revealed the existence of 21 ORFs encoding heat stress transcription factors (Hsfs). The project aims at the comparative analysis of these Hsfs with respect to their expression patterns, activator functions, intracellular localization and above all their interaction with other Hsfs (heterooligomerization) or other regulatory proteins (coregulators). A central aspect will be the characterization of the complex promoter architecture of the Arabidopsis hs genes and the role of hsf combinations for efficient activation of these genes (synergism between Hsfs). The results from the first three years period will serve as a basis for more advanced investigations of the Hsf network and its cross talks with the general stress signalling pathways of plants.

• DFG-Verfahren: Sachbeihilfen