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Staphylococcus aureus infection of endothelial cells
Antragsteller
Professor Dr. Andreas Peschel
Fachliche Zuordnung
Parasitologie und Biologie der Erreger tropischer Infektionskrankheiten
Förderung
Förderung von 2002 bis 2011
Projektkennung
Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5389431
Erstellungsjahr
2010
Zusammenfassung der Projektergebnisse
Keine Zusammenfassung vorhanden
Projektbezogene Publikationen (Auswahl)
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(2004) Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosokomial infections. Nature Med 10:243-245
Weidenmaier C, Kokai-Kun JF, Kristian SA, Chanturyia T, Kaibacher H, Gross M, Nicholson G, Neumeister B, Mond JJ, Peschel A
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(2005) DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect Immun 73:8033-8038
Weidenmaier C, Peschel A, Kempf VA, Lucindo N, Yeaman MR, Bayer AS
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(2005) Group B Streptococcus blood-brain barrier invasion depends upon proper cell surface anchoring of lipoteichoic acid. J Clin Invest 115:2499-2507
Doran KS, Engelson EJ, Khosravi A, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V
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(2005) Lack of wall teichoic acids in Staphylococcus aureus leads to reduced interactions with endothelial cells and to attenuated virulence in a rabbit model of endocarditis. J Infect Dis 191:1771-1777
Weidenmaier C, Peschel A, Xiong YQ, Kristian SA, Dietz K, Yeaman MR, Bayer AS
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(2005) Unusual trafficking pattern of Bartonella henselae-containing vacuoles in macrophages and endothelial cells. Cell Microbiol 7:1019-1034
Kyme PA, Haas A, Schaller M, Peschel A, Iredell J, Kempf VA
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(2006) Live cell imaging of phagosome maturation in Staphylococcus aureus-infected human endothelial cells: small colony variants are able to survive in lysosomes. Med Microbiol Immunol 195:185-194
Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M
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(2007) In vitro susceptibility of Staphylococcus aureus to thrombin-induced platelet microbicidal protein 1 (tPMP-1) is influenced by cell membrane phospholipid composition and asymmetry. Microbiology 153:1187-1197
Mukhopadhyay K, Whitmire W, Xiong YQ, Melden J, Jones T, Peschel A, Staubitz P, Adler- Moore J, McNamara PJ, Proctor RA, Yeaman MR, Bayer AS
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(2007) Suicidal erythrocyte death in sepsis. J Mol Med 85:269-277
Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Götz F, Döring G, Wieder T, Gulbins E, Lang F
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(2008) Differential roles of sortase-anchored surface proteins and wall teichoic acid in Staphylococcus aureus nasal colonization Int J Med Microbiol 298:505-513
Weidenmaier C, Kokai-Kun JF, Kulauzovic E, Thumm G, Köhler T, Stoll H, Götz F, Peschel A
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(2008) Teichoic acids and related cell wall glycopolymers in Grampositive physiology and host interaction. Nature Rev Microbiol 6:276-287
Weidenmaier C, Peschel A
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(2010) The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus. Int J Med Microbiol
Xia G, Köhler T, Peschel A