Staphylococcus aureus infection of endothelial cells

• Applicant: Professor Dr. Andreas Peschel
• Subject Area: Parasitology and Biology of Tropical Infectious Disease Pathogens
• Term: from 2002 to 2011
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5389431

• Final Report Year: 2010

Final Report Abstract

No abstract available

Publications

• (2004) Role of teichoic acids in Staphylococcus aureus nasal colonization, a major risk factor in nosokomial infections. Nature Med 10:243-245
  Weidenmaier C, Kokai-Kun JF, Kristian SA, Chanturyia T, Kaibacher H, Gross M, Nicholson G, Neumeister B, Mond JJ, Peschel A
  
• (2005) DltABCD- and MprF-mediated cell envelope modifications of Staphylococcus aureus confer resistance to platelet microbicidal proteins and contribute to virulence in a rabbit endocarditis model. Infect Immun 73:8033-8038
  Weidenmaier C, Peschel A, Kempf VA, Lucindo N, Yeaman MR, Bayer AS
  
• (2005) Group B Streptococcus blood-brain barrier invasion depends upon proper cell surface anchoring of lipoteichoic acid. J Clin Invest 115:2499-2507
  Doran KS, Engelson EJ, Khosravi A, Fedtke I, Equils O, Michelsen KS, Arditi M, Peschel A, Nizet V
  
• (2005) Lack of wall teichoic acids in Staphylococcus aureus leads to reduced interactions with endothelial cells and to attenuated virulence in a rabbit model of endocarditis. J Infect Dis 191:1771-1777
  Weidenmaier C, Peschel A, Xiong YQ, Kristian SA, Dietz K, Yeaman MR, Bayer AS
  
• (2005) Unusual trafficking pattern of Bartonella henselae-containing vacuoles in macrophages and endothelial cells. Cell Microbiol 7:1019-1034
  Kyme PA, Haas A, Schaller M, Peschel A, Iredell J, Kempf VA
  
• (2006) Live cell imaging of phagosome maturation in Staphylococcus aureus-infected human endothelial cells: small colony variants are able to survive in lysosomes. Med Microbiol Immunol 195:185-194
  Schröder A, Kland R, Peschel A, von Eiff C, Aepfelbacher M
  
• (2007) In vitro susceptibility of Staphylococcus aureus to thrombin-induced platelet microbicidal protein 1 (tPMP-1) is influenced by cell membrane phospholipid composition and asymmetry. Microbiology 153:1187-1197
  Mukhopadhyay K, Whitmire W, Xiong YQ, Melden J, Jones T, Peschel A, Staubitz P, Adler- Moore J, McNamara PJ, Proctor RA, Yeaman MR, Bayer AS
  
• (2007) Suicidal erythrocyte death in sepsis. J Mol Med 85:269-277
  Kempe DS, Akel A, Lang PA, Hermle T, Biswas R, Muresanu J, Friedrich B, Dreischer P, Wolz C, Schumacher U, Peschel A, Götz F, Döring G, Wieder T, Gulbins E, Lang F
  
• (2008) Differential roles of sortase-anchored surface proteins and wall teichoic acid in Staphylococcus aureus nasal colonization Int J Med Microbiol 298:505-513
  Weidenmaier C, Kokai-Kun JF, Kulauzovic E, Thumm G, Köhler T, Stoll H, Götz F, Peschel A
  
• (2008) Teichoic acids and related cell wall glycopolymers in Grampositive physiology and host interaction. Nature Rev Microbiol 6:276-287
  Weidenmaier C, Peschel A
  
• (2010) The wall teichoic acid and lipoteichoic acid polymers of Staphylococcus aureus. Int J Med Microbiol
  Xia G, Köhler T, Peschel A