Project Details
Desensitivierung von Makrophagen
Applicant
Professor Dr. Bernhard Brüne
Subject Area
Public Health, Healthcare Research, Social and Occupational Medicine
Term
from 2003 to 2009
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 5401418
Final Report Year
2009
Final Report Abstract
No abstract available
Publications
- Apoptotic cells promote macrophage survival by releasing the anti-apoptotic mediator sphingosine-1-phosphate. Blood 108:1635-1642, 2006
A. Weigert, A. Johann, A. von Knethen, H. Schmidt, G. Geisslinger and B. Brüne
- Recognition of apoptotic cells by macrophages activates the peroxisome proliferator activating receptor-y and attenuates the oxidative burst. Cell Death & Differ 13:1533-1540, 2006
A.M. Johann, A. von Knethen, D. Lindemann and B. Brüne
- Apoptotic cells induce arginase II in macrophages thereby attenuating nitric oxide production. FASEB J. 21:2704-2712, 2007
A.M. Johann, V. Barra, A. von Knethen, A. Weigert and B. Brüne
- PPAR attenuates cytosol to membrane translocation of PKCa to desensitize monocytes/macrophages. J. Cell Biol. 176:681-694, 2007
A. von Knethen, M. Seller, N. Tzieply, A. Weigert, A.M. Johann, C. Jennewein, R. Kohl and B. Brüne
- Apoptotic cell-derived SIP promotes HuR-dependent Cox-2 mRNA stabilization and protein expression. J. Immunology 180:1239-1248, 2008
A.M. Johann, W. Eberhardt, V. Barra, A. Weigert, A. von Knethen, J. Pfeilschifter and B. Brüne
- Sumoylation of PPARy by apoptotic cells prevents LPS-induced NCoR removal from kB binding sites mediating transrepression of pro-inflammatory cytokines. J. Immunology 181:5646-5652, 2008
C. Jennewein, A-M. Kuhn, M.V. Schmidt, V. Meilladec-Jullig, A. von Knethen, F. Gonzalez and B. Brüne
- Heme oxygenase-1 contributes to an alternative macrophage activation profile induced by apoptotic cell supernatants. Mol. Biol. Cell 20:1280-1288, 2009
N. Weis, A. Weigert, A. von Knethen and B. Brüne
- The liaison between apoptotic cells and macrophages - the end programs the beginning. Biol. Chem. 390:378-390, 2009
A. Weigert, C. Jennewein and B. Brüne