Biochemical and spectroscopic characterization of blue light receptors with LOV and BLUF-domain-type chromophores from microalgae and purple bacteria

• Antragstellerinnen / Antragsteller: Professor Dr. Peter Hegemann; Professorin Dr. Ilme Schlichting
• Fachliche Zuordnung: Biophysik
• Förderung: Förderung von 2004 bis 2011
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5470629

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• (2008) Algal sensory photoreceptors, Ann. Rev. Plant Biol. 59, 167-189
  Hegemann, Peter
  
• (2008) Hydrogen bond switching among flavin and amino acid side chains in the BLUF photoreceptor probed by ultrafast infrared spectroscopy. Biophys. J. 95, 4790-4802
  Bonetti, Cosimo; Mathes, Tilo; van Stokkum, Ivo H.M.; Mullen, Katharine M.; Groot, Marie-Louise; van Grondelle, Rienk; Hegemann, Peter & Kennis, John T.M.
  
• (2008) Molecular models predict light-induced glutamine tautomerization in BLUF photoreceptors. Biophys. J. 94, 3872-3879
  Domratcheva, Tatiana; Grigorenko, Bella L.; Schlichting, Ilme & Nemukhin, Alexander V.
  
• (2009) Photodynamics of blue-light-regulated phosphodiesterase BlrP1 protein from Klebsiella pneumoniae and its photoreceptor BLUF Chemical Physics 354, 130 - 141
  Tyagi, A.; Penzkofer, A.; Griese, J.; Schlichting, I.; Kirienko, Natalia V. & Gomelsky, Mark
  
• (2008) Sensory photoreceptors and Light Control of Flagellar Activity. Chlamydomonas Source Book. Vol. III Ed.G. Witman, pp. 391-425
  Hegemann, Peter & Berthold, Peter
  
• (2009) A genetically encoded photoactivatable Rac controls the motility of living cells. Nature 461, 104-108
  Wu, Yi I.; Frey, Daniel; Lungu, Oana I.; Jaehrig, Angelika; Schlichting, Ilme; Kuhlman, Brian & Hahn, Klaus M.
  
• (2009) Absorption and Emission Spectroscopic Characterisation of 8-Amino-Riboflavin. Chemical Physics 264, 19 - 30
  Tyagi, A.; Zirak, P.; Penzkofer, A.; Mathes, T.; Hegemann, P.; Mack, M. & Ghisla, S.
  
• (2009) Absorption and emission spectroscopic characterization of BLUF Protein Slr1694 from Synechocystis sp. PCC6803 with Roseoflavin Cofactor. J. Photochem. Photobiol. B. Biology 97, 61-70
  Zirak, P.; Penzkofer, A.; Mathes, T. & Hegemann, P.
  
• (2009) In vivo generation of flavoproteins with modified cofactors. J. Mol. Biol. 385, 1511-18
  Mathes, Tilo; Vogl, Christian; Stolz, Jürgen & Hegemann, Peter
  
• (2009) Mechanistic insights in Light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACa) Biological Chemistry 390, 1105-1111
  Looser, Jens; Schröder-Lang, Saskia; Hegemann, Peter & Nagel, Georg
  
• (2009) Photo-dynamics of Roseoflavin and Riboflavin in Aqueous and Organic Solvents. Chemical Phys. 358, 111-122
  Zirak, P.; Penzkofer, A.; Mathes, T. & Hegemann, P.
  
• (2009) Structure and Mechanism of a Bacterial Light-Regulated Cyclic Nucleotide Phosphodiesterase. Nature, 459: 1015-1018
  Barends, Thomas R. M.; Hartmann, Elisabeth; Griese, Julia J.; Beitlich, Thorsten; Kirienko, Natalia V.; Ryjenkov, Dmitri A.; Reinstein, Jochen; Shoeman, Robert L.; Gomelsky, Mark & Schlichting, Ilme
  
• (2009) The role of key amino acids in the photoactivation pathway of the Synechocystis Slr1694 BLUF domain. Biochemistry. 48(48):11458-69
  Bonetti, Cosimo; Stierl, Manuela; Mathes, Tilo; van Stokkum, Ivo H. M.; Mullen, Katharine M.; Cohen-Stuart, Thomas A.; van Grondelle, Rienk; Hegemann, Peter & Kennis, John T. M.
  
• 2009) The role of key amino acids in the photoactivation pathway of the Synechocystis Slr1694 BLUF domain. Biochemistry. 48(48):11458-69
  Bonetti, Cosimo; Stierl, Manuela; Mathes, Tilo; van Stokkum, Ivo H. M.; Mullen, Katharine M.; Cohen-Stuart, Thomas A.; van Grondelle, Rienk; Hegemann, Peter & Kennis, John T. M.
  
• (2010) Blue Light Induces Global and Localized Conformational Changes in the Kinase Domain of Full-Length Phototropin. Biochemistry. 49, 1024 – 1032
  Pfeifer, Anna; Mathes, Tilo; Lu, Yinghong; Hegemann, Peter & Kottke, Tilman
  
• (2010) Blue Light Induces Global and Localized Conformational Changes in the Kinase Domain of Full-Length Phototropin. Biochemistry. 49, 1024 – 1032
  Pfeifer, Anna; Mathes, Tilo; Lu, Yinghong; Hegemann, Peter & Kottke, Tilman
  
• (2010) Hindered Rotation of a Cofactor Methyl Group as a Probe for Protein-Cofactor Interaction JACS 132, 8935-8944
  Brosi, Richard; Illarionov, Boris; Mathes, Tilo; Fischer, Markus; Joshi, Monika; Bacher, Adelbert; Hegemann, Peter; Bittl, Robert; Weber, Stefan & Schleicher, Erik
  
• (2010) Photodegradation behaviour of roseoflavin in some equous solutions. Chemical Physics Chemical Physics 369 , 27 - 36
  Tyagi, A.; Penzkofer, A.; Mathes, T. & Hegemann, P.