Die funktionelle Bedeutung von ß-Catenin für die Myelinisierung und die Zytoarchitektur myelinisierter peripherer Nerven

• Applicant: Professor Dr. Peter Young
• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: from 2005 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5443664

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• 2005. An animal model for Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet 14 (23):3685-95
  Bonneick, S., M. Boentert, P. Berger, S. Atanasoski, N. Mantei, C. Wessig, K. V. Toyka, P. Young, and U. Suter
  
• 2006. Cell cycle inhibitors p21 and pI6 are required for the regulation of Schwann cell proliferation. Glia 53 (2): 147-57
  Atanasoski, S., D. Boller, L. De Ventura, H. Koegel, M. Boentert, P. Young, S. Werner, and U. Suter
  
• 2007. Mtmrl3/Sbf2-deficient mice: an animal model for CMT4B2. Hum Mol Genet 16 (24):2991-3001
  Tersar, K., M. Boentert, P. Berger, S. Bonneick, C. Wessig, K. V. Toyka, P. Young, and U. Suter
  
• 2008. Inhibition of N-cadherin and beta-catenin function reduces axon-induced Schwann cell proliferation. J Neurosci Res 86 (4):797-812
  Gess, B., H. Halfter, I. Kleffner, P. Monje, G. Athauda, P. M. Wood, P. Young, and I. B. Wanner
  
• 2008. Postnatal Schwann cell proliferation but not myelination is strictly and uniquely dependent on cyclin-dependent kinase 4 (cdk4). Mol Cell Neurosci 37 (3):519-27
  Atanasoski, S., M. Boentert, L. De Ventura, H. Pohl, C. Baranek, K. Beier, P. Young, M. Barbacid, and U. Suter