Neuronale Korrelate des strategischen Entscheidungsverhaltens und ihre Beeinflussung durch gelernte Hilflosigkeit
Zusammenfassung der Projektergebnisse
The main results of the experiments performed in the course of this project were: - The same brain structures are recruited before and after learning the decision-making task applied. Automatisation of performance is accompanied by a change in the degree of activation of the same brain areas, not with the recruitment of different brain areas as strategies are developed. - PTSD patients show slower learning as compared to healthy controls. This might be related to their reduced brain activation in reward-related brain structures following the experience of gains. - Learning decreases the feedback-related negativity, i.e., a relatively negative deflection at FCz after loss compared to gain feedback. These results lend further support to the view that the FRN is a reward prediction signal. - Learning progresses slower in subjects who are in the state of "learned helplessness", even if they reach 100% correct responses in the end. The relationship to neural processes is currently further analysed.
Projektbezogene Publikationen (Auswahl)
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(2006). Cortical Networks involved in Decision-Making: Independent Component Analysis and Source Localisation of Slow Cortical Potentials. In: 'FENS Forum Abstracts', A 159.2.
Fischmeister FP, Sailer U, Bauer H
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(2006). Neuronal activation changes when learning to make correct decisions: An fMRI study. In: 'SfN Abstract CD-ROM', 165.5/AA8
Sailer U, Robinson S, Fischmeister FP, Moser E, Kryspin-Exner I, Bauer H
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(2007). Imaging the changing role of feedback during learning in decision-making. Neuroimage, 37,1474-86
Sailer U, Robinson S, Fischmeister FP, Moser E, Kryspin-Exner I, Bauer H
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(2007). Neural dynamics of decision-making at different levels of outcome predictability. In: 'Cognitive Neuroscience Society Annual Meeting Program 2007', Cognitive Neuroscience Society, Suppl. Journal of Cognitive Neuroscience, pp. 112
Fischmeister FP, Sailer U, Bauer H
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(2007). Predictive eye and hand movements are differentially affected by schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 257: 413-422
Sailer U, Eggert T, Strassnig M, Riedel M, Sträube A
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(2008). A Resting State Network in the Basal Ganglia. ISMRM abstracts
Robinson S, Soldati N, Basso G, Sailer U, Jovicich J, Bruzzone L, Kryspin-Exner I, Bauer H, Moser E
