Gezielte Deletion großer Zytomegalievirus-Genomanteile zur Entwicklung abgeschwächter Virus-Vektoren für die Impfung von Primaten

• Applicant: Professor Dr. Luka Cicin-Sain
• Subject Area: Virology
• Term: from 2005 to 2008
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5452603

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates. Proc Natl Acad Sci U S A. 2007;104:19960-5
  Cicin-Sain L, Messaoudi I, Park B, Currier N, Planer S, Fischer M, Tackitt S, Nikolich-Zugich D, Legasse A, Axthelm MK, Picker LJ, Mori M, Nikolich-Zugich J
  
• Targeted deletion of regions rich in immune-evasive genes from the cytomegalovirus genome as a novel vaccine strategy. J Virol. 2007;81:13825-34
  Cicin-Sain L, Bubic I, Schnee M, Ruzsics Z, Mohr C, Jonjic S, Koszinowski UH