Project Details
Projekt
Decoding the input syntax of photosynthetic gene expression (D04*)
Subject Area
Plant Physiology
Term
since 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 270050988
The project uses large datasets, transcription factors, and promoter analyses to decode the input syntax of photo-synthetic gene expression. Transcription factors controlling photosynthesis are identified using machine learning based gene regulatory networks, validated using in vivo overexpression, and characterised with regard to relative binding specificity and interaction. Promoters are studied using binding data, comparative analyses in pangenomes and genomes of closely related species. The combined information is leveraged for synthetic promoter construc-tion and in vivo testing of hypotheses.
DFG Programme
CRC/Transregios
Applicant Institution
Ludwig-Maximilians-Universität München
Project Head
Professorin Dr. Andrea Bräutigam
