confocal laser-scanning-microscope

• Subject Area: Medicine
• Term: Funded in 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 550220235

In basic biomedical research, the detailed examination of cells and tissue samples contributes to a better understanding of disease mechanisms and the development of potential therapeutic approaches. Modern high-resolution microscopes are indispensable for deciphering complex structures in cells and organisms. The observation of cells in high spatial and temporal resolution in combination with the in-depth analysis of these images is of crucial importance for progress. Modern laser scanning microscopes (LSM) are now regarded as the standard in this field and not only enable the visualisation of microscopic structures, but also the use of innovative technologies that allow quantitative analyses of images in particular. The current 15-year-old inverted microscope with ApoTome technology at the Medical Clinic D (General Internal Medicine and Emergency Department as well as Renal and Hypertensive Diseases and Rheumatology) is often defective, not at a good technical level and can no longer be upgraded. At the UKM, the staff of the Medical Clinic B (Clinic for Gastroenterology, Hepatology, Endocrinology and Clinical Infectiology) and the Medical Clinic D conduct research in a laboratory complex. In order to save costs and at the same time keep up to date with the latest LSM technology, Clinic B and Clinic D are jointly applying for a new LSM. Coordination with the Münster Imaging Network of the University of Münster (MIN) has taken place.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: Konfokales Laser-Scanning-Mikroskop
• Instrumentation Group: 5090 Spezialmikroskope
• Applicant Institution: Universität Münster
• Leader: Professor Dr. Hermann Pavenstädt