Project Details
Projekt
Flow Induced Dispersion Analysis System
Subject Area
Polymer Research
Term
Funded in 2025
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 557867241
The Friedrich Schiller University (FSU) Jena is a leading institution for polymer research in Germany and Europe with a particular focus on polymeric materials for health and energy applications. Several projects at the FSU Jena are dedicated to the formulation and characterization of nanoparticulate drug carrier systems and their application in biology and medicine. In those projects, Flow Induced Dispersion Analysis (FIDA) can be used to study the stability, degradation rates and drug release profiles of nanocarriers and other nanomaterials in complex matrices in a high-throughput manner. It can further be utilized to analyze specific and selective binding of the drug carrier systems with proteins, antibodies or other molecules, providing valuable information on the interactions of biomolecules and particles with their surroundings. By enabling experiments in the native environment, a bridge can be built from formulation to in vivo experiments and accelerate ongoing research as well as enable the proposal of novel projects. In addition, the increase in efficiency through fast and accurate analyses with low required material and sample volumes can lead to long-term cost savings. FIDA is the necessary supplement in the workflow from polymer- to particle libraries that closes the gap from automated synthesis and high-throughput formulation to high-throughput automated biological in vitro screening methods, which are currently in development.
DFG Programme
Major Research Instrumentation
Major Instrumentation
Strömungsindizierte Dispersionsanalyse-System
Instrumentation Group
1380 Zubehör zur Chromatographie
Applicant Institution
Friedrich-Schiller-Universität Jena
