Advancing Nanoplastics Detection Exploiting UV Autofluorescence for Enhanced Sensitivity

• Applicant: Professor Dr. Jörg Enderlein
• Subject Area: Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry ; Analytical Chemistry
• Term: since 2025
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 568659119

The widespread use of plastic materials has led to a growing environmental crisis, with micro- and nanoplastics posing significant challenges. Nanoplastics, defined as plastic particles smaller than 1 μm, present the greatest threat due to their potential for deeper biological penetration and long-term persistence. While current analysis methods are effective for detecting particles larger than 3 μm, the identification and quantification of nanoplastics remain a major technological hurdle. The NanoPlasticsDetect project aims to break new ground in the quantitative detection of nanoplastics by exploiting time-resolved ultraviolet (UV) autofluorescence. Plastics emit intrinsic autofluorescence when illuminated in the UV, providing superior sensitivity to current Raman and infrared spectroscopies. The central objective is to improve the detection sensitivity thanks to this autofluorescence, targeting particles as small as 30 nm in diameter. A further original feature is the ability to distinguish between different types of plastic by exploiting their autofluorescence lifetime. This approach requires the development of advanced characterization techniques, as well as a deeper understanding of the UV photophysics of nanoplastics. The NanoPlasticsDetect project addresses this gap by integrating cutting-edge advances in spectroscopy, nanophotonics, and the synthesis of calibrated plastic nanoparticles. The project builds on the partners' recent progress and preliminary results, benefiting from a highly complementary expertise between the collaborating teams. This novel UV-based detection approach promises unprecedented sensitivity, the ability to detect nanoscale particles, and a direct, label-free detection method well-suited for in situ applications. By pushing the boundaries of nanoplastic detection, the project will provide critical tools for better understanding and quantifying this invisible yet pervasive form of pollution.

• DFG Programme: Research Grants
• International Connection: France
• Cooperation Partners: Dr. Patricia Merdy; Professor Dr. Jérome Wenger, Ph.D.