Heat-triggered protein-membrane interactions and biomolecular dynamics elucidated by time-resolved IR spectroscopy (B02)

• Subject Area: Biophysics ; Physical Chemistry of Molecules, Liquids and Interfaces, Biophysical Chemistry
• Term: since 2026
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 550938463

Cellular trigger responses rely on molecular interactions and dynamics. In this project, we develop tailored biomimetic membrane systems and combine them with time-resolved FTIR approaches and state of the art QCL spectroscopy. We apply these techniques to understand how heat modulates protein-membrane interactions and dynamics, induces conformational changes in proteins, and affects molecular condensation.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1756: Chemical and Biological Principles of Cellular Trigger Responses
• Applicant Institution: Universität Konstanz
• Project Head: Professorin Dr. Karin Hauser