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Institution
Max-Planck-Institut für medizinische Forschung
Address
Jahnstraße 29
69120 Heidelberg
Deutschland
GERiT
This institution in GERiT
69120 Heidelberg
Projects
Priority Programmes
Completed projects
Determining the Domain Linkages in the Myosin Motor
(Applicant
Holmes, Kenneth C.
)
Directed Evolution of the Dnak/ClpB chaperone system - towards substrate specific optimization and complementation with orthologous systems
(Applicant
Reinstein, Joachim
)
Herstellung und orientierte, dichroitische Anordnung von superparamagnetischen Core-Shell Clustern mit einem Cobaltkern und einer Goldhülle
(Applicant
Möller, Martin
)
Hydrodynamic manipulation of active transport along actin cortex models
(Applicant
Spatz, Joachim P.
)
Konstitutive und konditionelle Knock-outs des Glycinrezeptor Gens glyr alpha2: Untersuchungen zur Rolle der neonatalen Glycinrezeptorisoform bei der neuronalen Differenzierung und Synapsenbildung
(Applicant
Betz, Heinrich
)
Molekulare Grundlagen AMPA-Rezeptor vermittelter Plastizität
(Applicant
Sprengel, Rolf
)
Regulation of Glycine Neurotransmission by the Glial Glycine Transporter 1.
(Applicant
Eulenburg, Volker
)
Röntgenstrukturanalyse der Pyruvat-Formiatlyase (PFL)
(Applicant
Kabsch, Wolfgang
)
Untersuchungen zur funktionellen Heterogenität von GABAA-, GABAC- und Glyzin-Rezeptoren in der Retina von Säugern
(Applicant
Backus, Kurt Harald
)
Research Grants
Current projects
Virtual design of structured battery electrodes
(Applicant
Nieken, Ulrich
)
Completed projects
Cordintion of Spatial an Temporal Regulation of Integrin and EGFR Signaling
(Applicants
Olayioye, Monilola Afolabi
;
Spatz, Joachim P.
)
Darstellung, Quantifizierung und funktionelle Untersuchung der Regulation lokaler proteolytischer Aktivität bei der Tumorzellinvasion
(Applicant
Spatz, Joachim P.
)
Entwicklung neuer Lithographietechniken für die Nanometerskala basierend auf der Selbstorganisation dünner anorganisch-polymerer Hybridfilme
(Applicant
Möller, Martin
)
Molekulare Chaperone von Escherichia coli und Thermus thermophilus - Struktur und Funktion des DnaK/ClpB Systems
(Applicant
Reinstein, Joachim
)
The Actin-Myosin Interaction: Engineering a Strong Binding Form of Myosin II
(Applicant
Holmes, Kenneth C.
)
The Role of Glutamate and Glutamate Receptors in Mouse Models for Emotional Behaviors and Mood Disorders
(Applicants
Gass, Peter
;
Sprengel, Rolf
)
Research Fellowships
Completed projects
Covalent Labeling of Native Proteins Using a Reengineered Transferase Enzyme: Beyond Fusion Proteins
(Applicant
Hinner, Marlon Jakob
)
Importance of endocytic RabGTPases and endocytic recycling in virulence of the corn smut fungus Ustilago maydis
(Applicant
Lehr, Nina-Alexandra
)
Collaborative Research Centres
Current projects
Deciphering receptor-ligand interplay during rapid motility of Plasmodium sporozoites
(Project Heads
Frischknecht, Friedrich
;
Spatz, Joachim P.
)
Nanoscale characterization of integrin-virus interactions
(Project Heads
Cavalcanti-Adam, Elisabetta Ada
;
Grimm, Dirk
;
Spatz, Joachim P.
)
SFB 1129: Integrative Analysis of Pathogen – Replication and Spread
(Spokesperson
Kräusslich, Hans-Georg
)
SFB 1286: Quantitative Synaptology
(Spokesperson
Rizzoli, Ph.D., Silvio-Olivier
)
SFB 1638: Cellular membrane remodelling – how changing form creates function
(Spokesperson
Meinecke, Michael
)
The organization of the synaptic cytoskeleton
(Project Heads
D' Este, Elisa
;
Hell, Stefan W.
)
Completed projects
Characteristics and consequences of subcellular calcium signalling in spinal neurons and glia in chronic inflammatory and neuropathic pain
(Project Heads
Bading, Hilmar
;
Sprengel, Rolf
)
Chemical biology tools for infectious diseases research
(Project Heads
Johnsson, Kai
;
Schultz, Carsten
)
Control of synapse assembly and development of neuromuscular junctions in genetically engineered mouse models
(Project Heads
Müller, Ulrike
;
Witzemann, Veit
)
Der hypothalamische Pulsgenerator für GnRH Neurone: Wiedererwachen in der Pubertät
(Project Head
Seeburg, Peter H.
)
Funktionelle Entwicklung neuronaler Schaltkreise im olfaktorischen System vom Zebrafisch
(Project Head
Friedrich, Rainer
)
Funktion und Lokalisation zentralnervöser Glycintransporter und asoziierter Proteine
(Project Head
Betz, Heinrich
)
Genetische Analyse der axonalen Wegfindung in C. elegans
(Project Head
Hutter, Harald
)
Kombinatorische Methoden zur Untersuchung molekularer Organisationsprozesse; Kontrolle der Porphyrin-Reaktivität in Peroxidasen durch das Apo-Protein
(Project Head
Johnsson, Kai
)
Local and expanding glial activity patterns in memory-related networks of mice
(Project Head
Sprengel, Rolf
)
Mechanistische Untersuchungen an c-di-GMP Phosphodiesterasen
(Project Head
Schlichting, Ilme
)
Molekulare Chaperone von Escherichia coli und Thermus thermophilus - Struktur und Funktion von DnaK, GrpE und DnaJ
(Project Head
Reinstein, Joachim
)
Postnatal development of functional and structural properties of neocortical neurones with particular consideration of the barrel cortex
(Project Head
Feldmeyer, Dirk
)
Proteomic Analysis of Postsynaptic Receptor Complexes
(Project Head
Betz, Heinrich
)
Proteomic Analysis of Postsynaptic Receptor Complexes
(Project Heads
Betz, Heinrich
;
Kneussel, Ph.D., Matthias
)
SFB 426: Limbic Structures and Functions
(Spokesperson
Heinze, Hans-Jochen
)
SFB 488: Molecular and Cellular Bases of Neural Development
(Spokespersons
Unsicker, Klaus
;
Wittbrodt, Joachim
)
SFB 623: Molecular Catalysts: Structure and Functional Design
(Spokespersons
Gade, Lutz H.
;
Hofmann, Peter
)
SFB 636: Learning, Memory and Brain Plasticity: Implications for Psychopathology
(Spokesperson
Flor, Herta
)
SFB 1134: Functional ensembles: cellular components, patterned activity and plasticity of co-active neurons in local networks
(Spokesperson
Draguhn, Andreas
)
Structural characterization of radical based DNA repair processes
(Project Head
Schlichting, Ilme
)
Synaptic organizers at the developing neuromuscular junction
(Project Head
Witzemann, Veit
)
The role of GABA-A receptors in GnRH neurons and of olfactory bulb GnRH neurons of reproduction
(Project Head
Seeburg, Peter H.
)
The role of NMDA and AMPA receptors of excitatory neurons in hippocampal based memories
(Project Head
Sprengel, Rolf
)
Untersuchungen zur Regulation und zum Mechanismus der synaptischen Vesikelexozytose
(Project Head
Betz, Heinrich
)
CRC/Transregios
Current projects
Chemical biology and lipidomics for molecular switches
(Project Heads
Brügger, Britta
;
Johnsson, Kai
)
TRR 186: Molecular Switches: Spatio-temporal Control of Cellular Signal Transmission
(Spokespersons
Freund, Christian
;
Nickel, Walter
)
Completed projects
Surface patterning and functionalization strategies for targeted bone cell adhesion and response
(Project Heads
Cavalcanti-Adam, Elisabetta Ada
;
Spatz, Joachim P.
)
TRR 79: Materials for Tissue Regeneration within Systemically Altered Bone
(Spokespersons
Heiß, Christian
;
Schnettler, Reinhard
)
Research Training Groups
Completed projects
GRK 230: Molecular Cell Biology
(Spokesperson
Dobberstein, Bernhard
)
GRK 300: Pathogenic Microorganisms: Molecular Mechanisms and Genomic Approaches
(Spokesperson
Clayton, Christine Elizabeth
)
GRK 361: Neural Plasticity: Molecules, Structures, Functions
(Spokesperson
Zimmermann, Herbert
)
GRK 388: Biotechnology: Biochemical and Molecular Foundation
(Spokesperson
Wink, Michael
)
GRK 791: Neural Developmental and Degenerative Processes: Basic Research and Clinical Implications
(Spokesperson
Monyer, Hannah
)
Clusters of Excellence
Completed projects
EXC 81: Cellular Networks: From Analysis of Molecular Mechanisms to a Quantitative Understanding of Complex Functions (CellNetworks)
(Spokesperson
Kräusslich, Hans-Georg
)
Graduate Schools
Completed projects
GSC 249: The Hartmut Hoffmann-Berling International Graduate School of Molecular and Cellular Biology
(Spokesperson
Wittbrodt, Joachim
)
Clusters of Excellence (ExStra)
Current projects
EXC 2082: 3D Matter Made to Order (3DMM2O)
(Spokespersons
Bunz, Uwe F. H.
;
Selhuber-Unkel, Christine
;
Wegener, Martin
;
Wittbrodt, Joachim
)
Subinstitutions
Abteilung Biomedizinische Optik (aufgelöst)
Abteilung Biomolekulare Mechanismen
Abteilung Chemische Biologie
Wombacher Lab
Abteilung Molekulare Neurobiologie (aufgelöst)
Abteilung Zelluläre Biophysik
Göpfrich Group - Biophysical Engineering of Life
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