Bernhard-Nocht-Institut für Tropenmedizin (BNITM)
Address
Bernhard-Nocht-Straße 74
20359 Hamburg
Deutschland
GERiT
This institution in GERiT
20359 Hamburg
Projects
Priority Programmes
Current projects
Binding properties determine the cytoadhesion of Plasmodium falciparum infected erythrocytes with the host
(Applicants
Bruchhaus, Iris
;
Gutsmann, Thomas
)
Identification and characterization of novel factors mediating Plasmodium falciparum egress from the red blood cell
(Applicant
Gilberger, Tim-Wolf
)
Completed projects
Characterisation of the vacuolar compartment of malaria parasites within human red blood cells
(Applicant
Spielmann, Tobias
)
Determinanten der Temperaturstreß-Toleranz von Leishmania major und L. donovani
(Applicant
Clos, Joachim
)
Entamoeba histolytica-Proteine mit Funktionen für das Überleben und die Persistenz des Parasiten in Wirtsgeweben
(Applicant
Bruchhaus, Iris
)
Impact of the Heat Shock Protein 100 on the Intracellular Survival of Leishmania Amastigote Stages
(Applicant
Clos, Joachim
)
Molecular phylogenetic analysis of basal lineages of the Bilateria
(Applicant
Hausdorf, Bernhard
)
Struktur und biologische Funktion eines porenbildenden Proteins aus Leishmaninia donovani
(Applicant
Leippe, Matthias
)
Research Grants
Current projects
How does the parasite causing amoebiasis (Entamoeba histolytica) manage to invade through the intestine?
(Applicant
Bruchhaus, Iris
)
Regulation of immune cell populations and immune pathways by sex hormones
(Applicant
Altfeld, Marcus
)
Spatial and temporal EVOlution of LASSa virus in West Africa
(Applicant
Fichet-Calvet, Elisabeth
)
Completed projects
3unktionsanalyse des Thioredoxin-Systems von Plasmodium falciparum
(Applicant
Walter, Rolf Dieter
)
Analysis of Host-Parasite Cross-Talk based on the Bovine Model for Human Onchocerciasis, Onchocerca ochengi
(Applicants
Betzel, Christian
;
Brattig, Norbert
;
Liebau, Eva
;
Renz, Alfons
)
Biochemical and cell biological analysis of a virulence enhancing protein from Leishmania major; its impact on macrophage activity and gene expression
(Applicant
Clos, Joachim
)
Das Glyoxalase-System von Onchocerca volvolus und dem Model-Nematoden Caenorhabditis elegans
(Applicant
Liebau, Eva
)
Die Bedeutung von Cysteinproteasen und Cysteinproteaseinhibitoren für die Pathogenität von Entamoeba histolytica
(Applicant
Bruchhaus, Iris
)
Efflux und Synthese von Glutathion in mit Plasmodium falciparum infizierten Erythrozyten
(Applicant
Walter, Rolf Dieter
)
Elucidation of vitamin B1 and B6 biosynthesis in the human malaria parasite Plasmodium falciparum and their validation as a target for chemotherapy
(Applicant
Wrenger, Carsten
)
Emerging viruses in Africa: Molecular identification and characterisation of rodent-, shrew-, and bat-borne hantaviruses and assessment of their public health potential
(Applicant
Krüger, Detlev H.
)
Export determinants and pathways in protein trafficking in the human malaria parasite Plasmodium falciparum
(Applicant
Spielmann, Tobias
)
Functional analysis of the "Apical Membrane Antigen 1": Investigating the role of phosphorylation of the blood-stage vaccine candidate in the malaria parasite Plasmodium falciparum
(Applicant
Gilberger, Tim-Wolf
)
Functional characterization of the main integral protein components of the parasite-host cell interface of Plasmodium falciparum blood stages
(Applicant
Spielmann, Tobias
)
Genetic fine mapping and functional analysis of three chromosomal loci associated with resistance to severe falciparum malaria in humans
(Applicant
Timmann, Christian
)
Genetische Faktoren des Menschen und Erregervarianten als Determinanten für allergische Reaktion und Immunsuppression bei der Onchocerca-volvulus-Infektion
(Applicant
Horstmann, Rolf Dieter
)
Identification and characterisation of molecules involved in the pathogenicity of Entamoeba histolytica
(Applicant
Bruchhaus, Iris
)
Impact of infectious diseases on physical and mental development in African children
(Applicant
Schoppen, Ph.D., Stefanie
)
Inaktivierung reaktiver Sauerstoffspezies bei Entamoeba histolytica und Entamoeba dispar. Charakterisierung der Cystein-Proteasen von E. histolytica und E. dispar
(Applicant
Bruchhaus, Iris
)
Is elimination of human onchocerciasis possible? Epidemiological, entomological and parasitological studies in a bovine model in Cameroon
(Applicants
Brattig, Norbert
;
Renz, Alfons
;
Streit, Adrian
)
Klonierung einer sekretorischen Metallprotease und einer Serinprotease der Filarie Onchocerca volvulus und Charakterisierung der Genprodukte
(Applicant
Brattig, Norbert
)
Lassa Fever in Guinea and Sierra Leone: rodent control, and seasonality of human exposure to rodents
(Applicants
Borchert, Ph.D., Matthias
;
Fichet-Calvet, Elisabeth
)
Lassa Fever in Guinea and Sierra Leone: rodent-human cohabitation and disease control (LAROCS 2)
(Applicants
Borchert, Ph.D., Matthias
;
Fichet-Calvet, Elisabeth
)
Regulation der Expression und Aktivität der S-Adenosylmethionin-Decarboxylase von Nematoden
(Applicant
Walter, Rolf Dieter
)
Regulation des Polyamingehalts in Plasmodium falciparum
(Applicant
Walter, Rolf Dieter
)
The Evolution of Malaria Parasites and their Interactions with their Host Cell
(Applicants
Bruchhaus, Iris
;
Burmester, Thorsten
;
Spielmann, Tobias
)
Trans-signalling: A novel mechanism of Leishmania host cell immune evasion through the release of parasite signalling proteins
(Applicant
Clos, Joachim
)
Independent Junior Research Groups
Completed projects
Die Funktion von EBA140 für die Invasion von Plasmodium falciparum in den Wirtserythrozyten und die Identifizierung des EBA140 Rezeptors
(Applicant
Gilberger, Tim-Wolf
)
Research Units
Current projects
Coordination Funds
(Applicant
Altfeld, Marcus
)
FOR 5068: Sex differences in immunity
(Spokesperson
Altfeld, Marcus
)
Sex-specific responses of monocytes to infectious challenges
(Applicant
Lotter, Hannelore
)
Collaborative Research Centres
Completed projects
Einfluss der N-Glycosylierung der Hüllproteine der HIV-Subtypen A, B und C auf die Infektiosität und die Interaktion mit viralen Rezeptoren und Glycoproteinen auf Zellmambranen
(Project Head
Schreiber, Michael
)
Immune evasion strategies of Plasmodium liver stage parasites
(Project Head
Heussler, Volker Theo
)
Mechanisms underlying activation and polarisation of inflammatory monocytes and organ-specific regeneration in acute and chronic liver diseases
(Project Head
Lotter, Hannelore
)
Molekulare Interaktion von Siglecs mit sialylierten Liganden auf Trypanosoma cruzi und deren Bedeutung für die Regulation der Immunabwehr
(Project Heads
Fleischer, Bernhard
;
Jacobs, Ph.D., Thomas
)
SFB 470: Glycostructures in biological Systems - Synthesis and Function
(Spokesperson
Thiem, Joachim
)
SFB 841: Liver Inflammation: Infection, Immune Regulation and Consequences
(Spokesperson
Lohse, Ansgar W.
)
Research Fellowships
Completed projects
Integration von modulierter T-Zellaktivierung in T-Zell-Signaltransduktions-Komplexen
(Applicant
Moré, Solveig
)
Clinical Research Units
Completed projects
Vergleichende Untersuchungen zur mukosalen Immunpathogenese der tropischen Sprue, Cylosporiasis und Giardiasis bei Tropenrückkehrern mit chronischer Diarrhoe
(Applicant
Ullrich, Reiner
)
Major Instrumentation Initiatives
Completed projects
Analysis of highly dynamic subcellular mechanisms by Lattice Light Sheet Microscopy
Research Training Groups
Current projects
GRK 2771: Humans and Microbes: Reorganisation of Cell Compartments and Molecular Complexes during Infection
(Spokesperson
Aepfelbacher, Martin
)
GRK 2887: VISualization and structure in virus infectION (VISION)
(Spokesperson
Krey, Thomas
)
Completed projects
GRK 1459: Sorting and Interactions Between Proteins of Subcellular Compartments
(Spokesperson
Braulke, Thomas
)
Subinstitutions
Forschungsgruppe Pathogen
Abteilung Virologie
Arbeitsgruppe Virusimmunologie
Abteilung Zelluläre Parasitologie
Laborgruppe Ingrid Müller (aufgelöst)
Arbeitsgruppe Arbovirologie
Arbeitsgruppe Helminthen-Immunologie
Arbeitsgruppe Protozoen-Immunologie (Jacobs)
Sektion Epidemiologie und Diagnostik
Abteilung Infektionsepidemiologie
Sektion Implementationsforschung
Arbeitsgruppe Implementation medikamentöser Therapien
Arbeitsgruppe Medizinethnologie
Arbeitsgruppe One-Health-Bakteriologie
Sektion Medizinische Mikrobiologie ((aufgelöst)
Abteilung für Immunologie (aufgelöst)
Sektion Tropenmedizinische Forschung (aufgelöst)
