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Project Details

Institution

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Albert-Ludwigs-Universität Freiburg
BIOSS Centre for Biological Signalling Studies

Address Schänzlestraße 18
79104 Freiburg
Deutschland

GERiT This institution in GERiT

79104 Freiburg

Projects

Independent Junior Research Groups
- Completed projects
  - Chemical Tools for the Investigation of Phosphatases
    (Applicant Köhn, Maja )
Research Grants
- Current projects
  - i2TCR-Research: Immunotherapies inspired by TCR Research
    (Applicant Minguet, Ph.D., Susana )
- Completed projects
Research Units
- Current projects
  - FOR 2743: Mechanical Stress Protection
    (Spokesperson Höhfeld, Jörg )
  - FOR 2799: Receiving and Translating Signals via the gamma-delta T Cell Receptor
    (Spokesperson Prinz, Immo )
  - Improving γδ T cell-based immunotherapy against cancer by studying signal initiation of the γδTCR
    (Applicant Minguet, Ph.D., Susana )
  - Protein phosphatases as essential regulators of the mechanical stress response
    (Applicant Köhn, Maja )
- Completed projects
  - Regulation of the BAG3 chaperone network under mechanical stress
    (Applicants Höhfeld, Jörg ; Köhn, Maja )
Heisenberg Grants
- Current projects
  - Understanding T cells to develop novel Immunotherapies
    (Applicant Minguet, Ph.D., Susana )
Collaborative Research Centres
- Current projects
- Completed projects
  - Control of T cell motility by the biophysical properties of the tumor stroma
    (Project Head Minguet, Ph.D., Susana )
  - Die Rolle des Transkriptionsfaktors BOB.1 in der B-Zellentwicklung
    (Project Heads Nielsen, Ph.D., Peter ; Reth, Michael )
  - Gezielte Aktivierung von Lymphozyten durch variante Antigenrezeptoren
    (Project Head Reth, Michael )
  - Mechanisms of tumorigenesis and metastasis formation by the phos-phatase PRL-3
    (Project Head Köhn, Maja )
  - Modification and adaptor function of the B cell signaling proteins Syk and SHP-1
    (Project Head Reth, Michael )
  - N02: Developmental biology involving mechanisms of pattern formation, signaling and differentiation in embryogenesis and organogenesis of animal or plant models
    (Project Head Pyrowolakis, Giorgos )
  - Production and analysis of B-cell mutant mice with the Cre/loxP method
    (Project Head Reth, Michael )
  - Rekonstitution der Signalkaskaden vom B Zell Antigenrezeptor
    (Project Head Reth, Michael )
  - Struktur des B Zell-Antigenrezeptors und dessen Kopplung an Transducer Proteine
    (Project Heads Huber, Michael ; Reth, Michael )
Research Fellowships
- Completed projects
  - Decoding the role of Netrin-1 receptor shedding during cancer cell survival
    (Applicant Nikodemus, Ph.D., Denise )
  - Messung der Wechselwirkung von spannungs- und ligandengesteuerten Domänen in HCN-Ionenkanälen
    (Applicant Ulbrich, Maximilian )
CRC/Transregios
- Completed projects
  - The resting state of B lymphocytes and their Transition into early and late activation stages
    (Project Heads Minguet, Ph.D., Susana ; Reth, Michael )
  - The role of phosphatases in B cell autoimmunity
    (Project Heads Reth, Michael ; Warscheid, Bettina )
Priority Programmes
- Completed projects
  - Shedding light on myogenesis: using optogenetics to investigate myoblast differentiation and muscle regeneration
    (Applicants Kassel, Olivier ; Di Ventura, Ph.D., Barbara )
Major Research Instrumentation
- Completed projects
  - Fluorescence/patch clamp setup
Research Training Groups
- Current projects
  - GRK 2202: Transport across and into membranes
    (Spokesperson Friedrich, Thorsten )
- Completed projects
  - GRK 1104: From Cells to Organs: Molecular Mechanisms of Organogenesis
    (Spokesperson Neubüser, Annette )
International Research Training Groups
- Completed projects
  - GRK 1642: Soft Matter Science: Concepts for the Design of Functional Materials
    (Spokesperson Reiter, Günter )
Graduate Schools
- Completed projects
  - GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED)
    (Spokesperson Borner, Christoph )
Clusters of Excellence
- Completed projects
  - EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
    (Spokesperson Reth, Michael )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2189: CIBSS - Centre for Integrative Biological Signalling Studies
    (Spokespersons Driever, Wolfgang ; Hunte, Carola ; Kleine-Vehn, Jürgen ; Weber, Wilfried )

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