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Institution

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Albert-Ludwigs-Universität Freiburg
Medizinische Fakultät
Institut für Molekulare Medizin und Zellforschung

Address 79085 Freiburg
Deutschland

GERiT This institution in GERiT

79085 Freiburg

Projects

Priority Programmes
- Completed projects
  - Molecular detection of stem cell plasticity
    (Applicant von Kalle, Christof )
  - Untersuchungen zur Rolle der lysosomalen Cysteinpeptidase Cathepsin L bei Proliferation und Differenzierung epidermaler Keratinozyten
    (Applicant Reinheckel, Thomas )
Research Grants
- Current projects
  - The role of Gab2 in leukemia stem cells and mast cells in the context of chronic myeloid leukemia.
    (Applicant Halbach, Sebastian )
- Completed projects
Independent Junior Research Groups
- Completed projects
  - A comprehensive and functional analysis of B-Raf signalling
    (Applicant Brummer, Tilman )
  - Substrate Profiling of Cysteine Proteases in Physiology and Pathology
    (Applicant Schilling, Oliver )
Research Fellowships
- Completed projects
Research Units
- Completed projects
  - FOR 2036: New Insights into Bcl-2 Family Interactions: From Biophysics to Function
    (Spokesperson Brunner, Thomas )
  - Signal integration by phosphorylation and complex formation of Bim and Puma
    (Applicant Borner, Christoph )
Heisenberg Fellowships
- Completed projects
  - Mechanistic analysis of Vascular Endothelial Growth Factor (VEGF) Internal Ribosomal Entry Site (IRES)-mediated translation in tumorigenesis
    (Applicant Thoma, Christian )
  - Signal transduction in tumour development and drug resistance
    (Applicant Brummer, Tilman )
Heisenberg Professorships
- Completed projects
  - Signal transduction in tumour development and drug resistance
    (Applicant Brummer, Tilman )
Heisenberg Grants
- Completed projects
  - Heisenberg-Professorship - Signal transduction in tumour development and drug resistance
    (Applicant Brummer, Tilman )
Collaborative Research Centres
- Current projects
  - Overcoming immune evasion of BRAF mutant colorectal cancer
    (Project Head Brummer, Tilman )
- Completed projects
  - Administration of the Collaborative Research Center
    (Project Head Peters, Christoph )
  - Control of tumor cell proliferation, migration and invasion by SNAIL1-induced changes in Wnt and BMP pathway activity
    (Project Head Hecht, Andreas )
  - Role of Bim and apoptosis in the development of polycystic kidney disease (PKD)
    (Project Head Borner, Christoph )
  - SFB 364: Molecular and Cellular Bases of Tumor Therapy
    (Spokesperson Peters, Christoph )
  - SFB 850: Control of Cell Motility in Morphogenesis, Cancer Invasion and Metastasis
    (Spokesperson Peters, Christoph )
  - Therapeutic impact of protease deficiency on breast cancer invasion and metastasis
    (Project Heads Peters, Christoph ; Reinheckel, Thomas )
  - Understanding the role of the BRAFV600E oncoprotein in colorectal cancer initiation and metastasis
    (Project Head Brummer, Tilman )
  - Untersuchungen zum Einfluß lysosomaler Cystein-Proteinasen auf Tumorinvasion und -metastasierung
    (Project Head Peters, Christoph )
  - Zentrale Verwaltung des SFB
    (Project Head Peters, Christoph )
Major Research Instrumentation
- Completed projects
  - Hybrid Quadrupol Massenspektrometer mit vorgeschaltetem UHPLC-System
  - Kleintierultraschallgerät
WBP Return Grant
- Completed projects
  - Rückkehrstipendium
    (Applicant Beyes, Ph.D., Sven )
CRC/Transregios
- Current projects
  - Host cell decisions between apoptosis, necroptosis and survival after infections with Herpes simplex virus-1 (HSV-1)
    (Project Head Borner, Christoph )
  - The role of SPATA2 for the decision between cell death and survival
    (Project Head Maurer, Ulrich )
Research Training Groups
- Current projects
  - GRK 2344: MeInBio - BioInMe: Exploration of spatio-temporal dynamics of gene regulation using high-throughput and high-resolution methods
    (Spokesperson Vogel, Tanja )
  - GRK 2606: Understanding protease functions in cellular pathways through discovery and analysis of protease substrates (ProtPath)
    (Spokesperson Reinheckel, Thomas )
- Completed projects
  - GRK 1104: From Cells to Organs: Molecular Mechanisms of Organogenesis
    (Spokesperson Neubüser, Annette )
Graduate Schools
- Completed projects
  - GSC 4: Molecular Cell Research in Biology and Medicine (MOBILMED)
    (Spokesperson Borner, Christoph )
Clusters of Excellence
- Completed projects
  - EXC 294: Centre for Biological Signalling Studies (bioss) - From Analysis to Synthesis
    (Spokesperson Reth, Michael )

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