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Institution
Universitätsklinikum Bonn (UKB)
Biomedical Center (BMZ)
Institute of Structural Biology
Address
Venusberg-Campus 1
53127 Bonn
Deutschland
GERiT
This institution in GERiT
53127 Bonn
Projects
Research Grants
Current projects
Biochemical and structural analysis of the NLRP3 inflammasome
(Applicant
Geyer, Matthias
)
Discovery of Chemical and Biological Tools for Reprogramming the Transcription Factor BCL6 Through Chemically Induced Proximity Modalities
(Applicants
Nowak, Ph.D., Radoslaw
;
Steinebach, Christian
)
Molecular determinants of sialic acid transport in pathogenic and commensal bacteria
(Applicant
Hagelueken, Gregor
)
Structural and biochemical characterization of the CRISPR-Lon/T complex
(Applicant
Hagelueken, Gregor
)
Completed projects
Analyse der Komplexbildung und Membranassoziation der heterotetramen Adaptorproteine AP -1 und AP-2 mit Cargoproteinen HIV-1 Nef und CD4
(Applicant
Geyer, Matthias
)
Biochemische Charakterisierung und Struktur-Funktionsbeziehung der GTP-bindenden Domäne des Trans-Aktivatorproteins CIITA
(Applicant
Geyer, Matthias
)
Biochemische und strukturbiologische Analyse der Regulation des humanen Transkriptionselongationsfaktors P-TEFb
(Applicant
Geyer, Matthias
)
Design und Charakterisierung eines Moleküls zur Inhibierung des HIV Pathogenesefaktors Nef
(Applicant
Geyer, Matthias
)
Integrated Approach to Study Structure, Function and Dynamics of TRAP Transporters
(Applicant
Hagelueken, Gregor
)
Regulationsmechanismen und physiologische Funktion des Diaphanous Formins FHOD1
(Applicants
Fackler, Ph.D., Oliver T.
;
Geyer, Matthias
)
Role of the Diaphanous Formin FHOD1 and its interaction with nesprin-2-giant in nuclear migration
(Applicants
Fackler, Ph.D., Oliver T.
;
Geyer, Matthias
)
Structural and functional analysis of transcription regulating kinases Cdk10 and Cdk11
(Applicant
Geyer, Matthias
)
Priority Programmes
Completed projects
Structure-function analysis of mammalian formins FMNL1 and FMNL2
(Applicant
Geyer, Matthias
)
Trityl Radicals: New Spin Labels for Nanometer Distance Measurements with higher Sensitivity, at Room Temperature and within Cells
(Applicants
Hagelueken, Gregor
;
Schiemann, Olav
)
Major Research Instrumentation
Completed projects
Device for the determination of binding affinities of molecules by the measurement of surface plasmon resonance spectroscopy
Collaborative Research Centres
Completed projects
Coordination of protoporphyrin IX-iron-complexes to hem-regulated proteins studied by EPR-spectroscopy and X-ray crystallography
(Project Heads
Hagelueken, Gregor
;
Imhof, Diana
;
Schiemann, Olav
)
CRC/Transregios
Current projects
Higher-order structures of ligand bound RIG-I and cGAS
(Project Heads
Geyer, Matthias
;
Schlee, Martin
)
Completed projects
Role of the VraDE transporter in differential susceptibility of S. aureus towards guanidine-containing lipopeptides and other cell wall targeting antibiotics
(Project Heads
Geyer, Matthias
;
Groß, Harald
;
Schneider, Tanja
)
Clusters of Excellence (ExStra)
Current projects
EXC 2151: ImmunoSensation2 - the immune sensory system
(Spokespersons
Hartmann, Gunther
;
Kolanus, Waldemar
;
Latz, Eicke
;
Schultze, Joachim L.
)
Additional Information
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