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Institution
Universität Leipzig
Institut für Biochemie
Arbeitsgruppe Biochemie und Molekularbiologie
Address
Brüderstraße 34
04103 Leipzig
Deutschland
GERiT
This institution in GERiT
04103 Leipzig
Projects
Research Grants
Current projects
CCA-adding enzymes with increased substrate affinities: strategies and consequences for adaptation to RNA substrates
(Applicants
Mörl, Mario
;
Prohaska, Sonja
)
Design of synthetic RNase-resistant RNA structures and their integration in novel riboswitch constructs to regulate mRNA stability
(Applicant
Mörl, Mario
)
High-throughput structure probing of RNA based on specific ligation of cyclo-phosphate ends combined with deep sequencing
(Applicants
Mörl, Mario
;
Stadler, Peter Florian
)
Miniaturized armless tRNAs – function, interaction, modifications
(Applicants
Mörl, Mario
;
Stadler, Peter Florian
)
RNA-seq-based screening for active self-cleaving ribozymes and transcriptome-wide assessment of their regulatory functions
(Applicants
Fallmann, Ph.D., Jörg
;
Weinberg, Christina E.
)
Unravelling the biological roles of self-cleaving ribozymes in bacteria
(Applicant
Weinberg, Christina E.
)
Completed projects
Analysis of structure-function relation in nucleotidyltransferases
(Applicant
Mörl, Mario
)
Co-evolution of bizarre armless tRNAs and their maturation enzymes in Enoplea
(Applicant
Mörl, Mario
)
Regulatory function of the tRNA 3'-end in E. coli
(Applicants
Czech, Andreas
;
Mörl, Mario
)
Synthetic riboswitches: design of multi-ligand switches and novel regulatory principle
(Applicants
Mörl, Mario
;
Stadler, Peter Florian
)
tRNA editing in S. cerevisiae: Isolation and Identification of the responsible nucleotidyltransferase
(Applicant
Mörl, Mario
)
Unusual RNA-polymerases: reaction mechanism and substrate specificity of tRNA nucleotidyltransferases
(Applicants
Mörl, Mario
;
Prohaska, Sonja
)
Priority Programmes
Completed projects
Evolution of Chemical Modifications: from tRNAs to Transcriptome-Wide Surveys
(Applicants
Mörl, Mario
;
Stadler, Peter Florian
)
In vitro recapitulation of the evolution of tRNA nucleotidyltransferases (CCA-adding enzymes)
(Applicant
Mörl, Mario
)
Major Research Instrumentation
Completed projects
Autoradiographie- und Fluoreszenzimager
Research Fellowships
Completed projects
Quest for riboswitches in eukaryotes and identification of orphan riboswitch ligands
(Applicant
Weinberg, Christina E.
)
Additional Information
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