Universitätsmedizin Göttingen
Zentrum Pharmakologie und Toxikologie
Institut für Klinische Pharmakologie
Address
Robert-Koch-Straße 40
37075 Göttingen
Deutschland
GERiT
This institution in GERiT
37075 Göttingen
Projects
Research Grants
Current projects
Functional characterization and identification of the gene of the proton-organic cation antiporter
(Applicant
Brockmöller, Jürgen
)
Investigating the mechanisms of cardiomyocyte-mediated crosstalk in vascular cell remodeling and cellular stress - towards regenerative therapies
(Applicants
Sossalla, Samuel
;
Zelarayan-Behrend, Laura C.
)
Completed projects
Defining the role of KLF15 in regulation of the Wnt Signaling in the healthy and diseased heart
(Applicant
Zelarayan-Behrend, Laura C.
)
Effects of genetic polymorphisms in the organic cation transporter OCT1 on cellular uptake and metabolism of antidepressants and other drugs
(Applicant
Tzvetkov, Mladen Vassilev
)
SMAD7 expression and radiotoxicity: Clarification of mechanisms for the observed correlation in fibroblasts with clinical toxicity and development of a cell model for evaluation of pharmacological interventions
(Applicant
Schirmer, Markus
)
Clinical Research Units
Completed projects
Analysis of difficult-to-treat psychosis: Clinical pharmacology and functional pharmacogenetics
(Applicant
Brockmöller, Jürgen
)
Biomarkers for toxicity from and response to pre-operative radiochemotherapy: clinical, pharmacogenomic, and functional analyses
(Applicant
Wolff, Hendrik A.
)
Collaborative Research Centres
Current projects
Detrimental effects of atrial fibrillation on right ventricular function in pulmonary hypertension – mechanisms and therapeutic targets
(Project Heads
Sossalla, Samuel
;
Zelarayan-Behrend, Laura C.
)
Completed projects
Cardiomyocyte Wnt/β-catenin complex activity in pathological remodeling - a tissue-specific therapeutic target
(Project Head
Zelarayan-Behrend, Laura C.
)
Supporting CRC 1002 research data integration, visualization and reusability
(Project Heads
Nußbeck, Sara
;
Zelarayan-Behrend, Laura C.
)
Research Training Groups
Completed projects
GRK 426: Molecular Basis of Therapy
(Spokesperson
Birchmeier, Walter
)
GRK 1034: The Impact of Inherited Polymorphismus in Oncology: From Basic Science to Clinical Application
(Spokesperson
Brockmöller, Jürgen
)