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Institution

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Universitätsklinikum Magdeburg A.ö.R.
Zentrum für Innere Medizin
Klinik für Hämatologie und Onkologie

Address Leipziger Straße 44
39120 Magdeburg
Deutschland

GERiT This institution in GERiT

39120 Magdeburg

Projects

Research Grants
- Current projects
  - Re-education of immunosuppressive myeloid cells to increase the efficacy of chimeric antigen receptor (CAR) T cells.
    (Applicants Bruns, Heiko ; Mougiakakos, Dimitrios )
- Completed projects
  - FLT3-ITD variants in AML - impact on disease biology and treatment outcome
    (Applicants Bullinger, Lars ; Fischer, Thomas )
  - The immunometabolic reprogramming of human T-cells by chronic lymphocytic leukemia-derived exosomes
    (Applicant Mougiakakos, Dimitrios )
Research Fellowships
- Completed projects
  - Evaluation der Rolle des Thioredoxin (TRX) als Mediator antioxidativer und zugleich immunsuppressiver Funktionen in humanen regulatorischen T-Zellen (Tregs)
    (Applicant Mougiakakos, Dimitrios )
Research Units
- Current projects
  - FOR 2886: PANDORA - Pathways triggering AutoimmuNity and Defining Onset of early Rheumatoid Arthritis
    (Spokesperson Krönke, Gerhard )
- Completed projects
  - Metabolic and dietary control of mesenchymal tissue priming and persistence of arthritis
    (Applicants Hoffmann, Markus ; Mougiakakos, Dimitrios )
Collaborative Research Centres
- Completed projects
  - Aberrant activation of β1 and β2 integrins on leukocytes in JAK2-V617F mutated disease
    (Project Heads Fischer, Thomas ; Heidel, Florian )
CRC/Transregios
- Current projects
  - Metabolic dysregulations in EMT-driven metastatic colonisation
    (Project Heads Brabletz, Thomas ; Mougiakakos, Dimitrios )
  - Metabolic stress related immune alterations with impact on graft-versus-leukemia effect in allogeneic stem cell transplantation
    (Project Heads Mackensen, Andreas ; Mougiakakos, Dimitrios )
Research Training Groups
- Current projects
  - GRK 2408: Maladaptive processes across physiological barriers in chronic diseases
    (Spokesperson Naumann, Michael )
  - GRK 2599: FAIR - Fine-Tuners of the Adaptive Immune Response
    (Spokesperson Zaiss, Mario M. )
- Completed projects
  - GRK 1167: Cell-cell Communication in Neural and Immune Systems: Topological Organisation of Signal Transduction
    (Spokesperson Naumann, Michael )

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