Philipps-Universität Marburg
Zentrum für Tumor- und Immunbiologie (ZTI)
Institut für molekulare Onkologie
Address
Hans-Meerwein-Straße 3
35043 Marburg
Deutschland
GERiT
This institution in GERiT
35043 Marburg
Projects
Clinical Research Units
Completed projects
Exploring cancer therapies based on p53-reactivating drugs using shRNA barcode screening
(Applicant
Wanzel, Michael
)
Role of p73 for drug resistance
(Applicant
Stiewe, Thorsten
)
Research Grants
Current projects
Mutant p53 mouse cancer models using somatic CRISPR base editing
(Applicant
Stiewe, Thorsten
)
Completed projects
Functional annotation of the TP53 mutome by CRISPR/Cas9-based saturating mutagenesis
(Applicant
Stiewe, Thorsten
)
mTOR-mediated metabolic vulnerability of chemotherapy resistant cancer
(Applicant
Wanzel, Michael
)
Role of DNA binding cooperativity for tumor suppression by p53
(Applicant
Stiewe, Thorsten
)
Tumor addiction to late p53 inactivation
(Applicant
Timofeev, Oleg
)
CRC/Transregios
Completed projects
Gene expression profiling and functional genomics
(Project Heads
Ade, Carsten Patrick
;
Wanzel, Michael
)
Ras-dependent pathways in human cancer
(Project Heads
Gaubatz, Stefan
;
Stiewe, Thorsten
)
Role of p53 core domain interactions for target gene selection and tumor suppression
(Project Head
Stiewe, Thorsten
)
Role of p73-directed chromatin alterations for neuroendocrine differentiation in small cell lung cancer
(Project Head
Stiewe, Thorsten
)
Role of the Myc/Miz1 interaction in the co-operation of Ras and Myc
(Project Heads
Eilers, Martin
;
Elsässer, Hans-Peter
;
Wanzel, Michael
)
Priority Programmes
Completed projects
Epigenetics of the nuclear oncoprotein Ski in AML
(Applicant
Neubauer, Andreas
)
Research Training Groups
Current projects
GRK 2573: The inflammatory tumor secretome – from understanding to novel therapies
(Spokesperson
Pogge von Strandmann, Elke
)
