Project Details

Professor Dr. Thorsten Stiewe

Address Philipps-Universität Marburg
Zentrum für Tumor- und Immunbiologie (ZTI)
Institut für molekulare Onkologie
Hans-Meerwein-Straße 3
35043 Marburg

Projects

As Applicant
- Current projects
  - Mutant p53 mouse cancer models using somatic CRISPR base editing (Research Grants)
- Completed projects
  - Role of p73 for drug resistance (Clinical Research Units)
  - Role of DNA binding cooperativity for tumor suppression by p53 (Research Grants)
  - Functional annotation of the TP53 mutome by CRISPR/Cas9-based saturating mutagenesis (Research Grants)
As Participating Researcher
- Current projects
  - GRK 2573: The inflammatory tumor secretome – from understanding to novel therapies (Research Training Groups)
As Project Head
- Completed projects
  - Role of p53 core domain interactions for target gene selection and tumor suppression (CRC/Transregios)
  - Ras-dependent pathways in human cancer (CRC/Transregios)
  - Role of p73-directed chromatin alterations for neuroendocrine differentiation in small cell lung cancer (CRC/Transregios)
As Participating Person
- Completed projects
  - Epigenetics of the nuclear oncoprotein Ski in AML (Priority Programmes)

Servicenavigation

Hauptnavigation

Professor Dr. Thorsten Stiewe

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Thorsten Stiewe

Additional Information

Textvergrößerung und Kontrastanpassung