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Professor Dr. Gerhard Sengle

Address Uniklinik Köln
Klinik und Poliklinik für Kinder- und Jugendmedizin
Kerpener Straße 62
50937 Köln

Projects

As Applicant
- Current projects
  - Controlling collagen deposition by fibroblasts in cutaneous fibrosis by targeting TANGO1 function (Research Grants)
  - Metabolically active hormones derived from the musculoskeletal system (Research Units)
  - Microenvironmental regulation of muscle homeostasis and its role in musculoskeletal diseases (Research Units)
- Completed projects
  - Identifikation und Charakterisierung neuer Liganden für Fibrillin durch Screenen der Propeptide aller Mitglieder aus der Familie der humanen TGFß Wachstumsfaktoren (Research Fellowships)
  - Extracellular regulation of growth factors of the transforming growth factor beta superfamily by fibrillin (Research Grants)
As Project Head
- Current projects
  - Dysregulated extracellular signalling pathways in aortic aneurysm formation in Marfan syndrome and related disorders (CRC/Transregios)
  - Animal models (CRC/Transregios)
  - Integrated Research Training Group Aortic Disease (CRC/Transregios)
- Completed projects
  - Structure-function relationships of Hsp47/SERPINH1 and its role in skin fibrosis (Collaborative Research Centres)
  - Extracellular fibrillin microfibrils as multifunctional scaffolds integrating growth factor signalling in the skin (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Role of Integrin-linked kinase in skin homeostasis and carcinogenesis (Research Grants)

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