KFO 136:  Regeneration und Adaption im kardiovaskulären System: Molekulare Signalwege und Mechanismen

• Fachliche Zuordnung: Medizin
• Förderung: Förderung von 2005 bis 2017
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 13001445

• Erstellungsjahr: 2014

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus - Restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Circulation, Vol. 116. 2007, Issue 2, pp. 163–173.
  Sorrentino S.A., Bahlmann F.H., Besler C., Muller M., Schulz S., Kirchhoff N., Doerries C., Horvath T., Limbourg A., Limbourg F., Fliser D., Haller H., Drexler H., Landmesser U.
  
• Erythropoietin and the endothelium: a promising link? European Journal of Clinical Investigation, Vol. 38. 2008, Issue 7, pp. 457-461.
  Fliser D., Bahlmann F.H.
  
• Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia. Nature Protocols, Vol. 4. 2009, pp. 1737–1748.
  Limbourg A., Korff T., Napp L.C., Schaper W., Drexler H., Limbourg F.P.
  
• Continuous glycoprotein-130-mediated signal transducer and activator of transcription-3 activation promotes inflammation, left ventricular rupture, and adverse outcome in subacute myocardial infarction. Circulation, Vol. 122. 2010, Issue 2, pp. 145–155.
  Hilfiker-Kleiner D., Shukla P., Klein G., Schaefer A., Stapel B., Hoch M., Muller W., Scherr M., Theilmeier G., Ernst M., Hilfiker A., Drexler H.
  
• Conditional transgenic expression of fibroblast growth factor 9 in the adult mouse heart reduces heart failure mortality after myocardial infarction. Circulation, Vol. 123.2011, Issue 5, pp. 504–514.
  Korf-Klingebiel M., Kempf T., Schluter K.D., Willenbockel C., Brod T., Heineke J., Schmidt V.J., Jantzen F., Brandes R.P., Sugden P.H., Drexler H., Molkentin J.D., Wollert K.C.
  
• GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptorlike kinase 5 signaling. Journal of Biological Chemistry, Vol. 286. 2011, Issue 7, pp. 5680-5690.
  Froese N., Kattih B., Breitbart A., Grund A., Geffers R., Molkentin J.D., Kispert A., Wollert K.C., Drexler H., Heineke J.
  
• Tbx18 function in epicardial development. Cardiovascular Research, Vol. 96. 2012, Issue 3, pp. 476–483.
  Greulich F., Farin H.F., Schuster-Gossler K., Kispert A.
  
• Reduction of STAT3 expression induces mitochondrial dysfunction and autophagy in cardiac HL-1 cells. European Journal of Cell Biology, Vol. 92. 2013, Issue 1, pp. 21-29.
  Elschami M., Scherr M., Philippens B., Gerardy-Schahn R.
  
• Toll-like receptor 2/6 agonist macrophageactivating lipopeptide-2 promotes reendothelialization and inhibits neointima formation after vascular injury. Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 33. 2013, Issue 9, pp. 2097–2104.
  Grote K., Sonnenschein K., Kapopara P.R., Hillmer A., Grothusen C., Salguero G., Kotlarz D., Schuett H., Bavendiek U., Schieffer B.
  
• Thrombomodulin's lectin-like domain reduces myocardial damage by interfering with HMGB1-mediated TLR2 signalling. Cardiovascular Research, Vol. 101. 2014, Issue 3, pp. 400–410.
  Herzog C., Lorenz A., Gillmann H.J., Chowdhury A., Larmann J., Harendza T., Echtermeyer F., Muller M., Schmitz M., Stypmann J., Seidler D.G., Damm M., Stehr S.N., Koch T., Wollert K.C., Conway E.M., Theilmeier G.