Molecular Pathology and Embryology of HOXD Related Limb Malformations

• Applicant: Professor Dr. Stefan Mundlos
• Subject Area: Human Genetics
• Term: from 2009 to 2012
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 134245387

• Final Report Year: 2013

No abstract available

Publications

• Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. Journal of Clinical Investigation, Vol. 120. 2010, Issue 6, pp. 1994–2004.
  Villavicencio-Lorini, Pablo; Kuss, Pia; Friedrich, Julia; Haupt, Julia; Farooq, Muhammed; Türkmen, Seval; Duboule, Denis; Hecht, Jochen & Mundlos, Stefan
  
• Mesomelic dysplasia Kantaputra type is associated with duplications of the HOXD locus on chromosome 2q. European Journal of Human Genetics, Vol. 18. 2010, pp. 1310–1314.
  Kantaputra, Piranit N; Klopocki, Eva; Hennig, Bianca P; Praphanphoj, Verayuth; Le Caignec, Cédric; Isidor, Bertrand; Kwee, Mei L; Shears, Deborah J & Mundlos, Stefan
  
• Distinct global shifts in genomic binding profiles of limb malformation associated HOXD13 mutations. Genome Research, Vol. 23. 2013, pp 2091-2102.
  Ibrahim, Daniel M.; Hansen, Peter; Rödelsperger, Christian; Stiege, Asita C.; Doelken, Sandra C.; Horn, Denise; Jäger, Marten; Janetzki, Catrin; Krawitz, Peter; Leschik, Gundula; Wagner, Florian; Scheuer, Till; Schmidt-von Kegler, Mareen; Seemann, Petra; Timmermann, Bernd; Robinson, Peter N.; Mundlos, Stefan & Hecht, Jochen
  
• Regulation of Cell Polarity in the Cartilage Growth Plate and Perichondrium of Metacarpal Elements by HOXD13 and WNT5A. Developmental Biology, Vol. 385. 2014, Issue 1, pp. 83–93.
  Kuss, Pia; Kraft, Katerina; Stumm, Jürgen; Ibrahim, Daniel; Vallecillo-Garcia, Pedro; Mundlos, Stefan & Stricker, Sigmar