Role of SUMO-targeted ubiquitylation in the control of mitochondrial fission (A02)

• Subject Area: Cell Biology
• Term: from 2016 to 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 269925409

Mitochondria form a highly dynamic intracellular network, which is regulated by fusion and fission events. In this project, we will investigate the role of SUMO and of ubiquitin ligases recognising SUMO modified proteins (ULS) in the regulation of mitochondrial fission. The long-term goal of this project is to understand the regulation of mitochondrial fission in response to physiological needs by a cross talk of SUMO and ubiquitin modifications.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1218: Mitochondrial regulation of cellular function
• Applicant Institution: Universität zu Köln
• Project Head: Professor Dr. Jürgen Dohmen